{"id":"W4408370589","doi":"10.3390/tropicalmed10030075","title":"Generalized Treatment as Prevention Plus Focused Pre-Exposure Prophylaxis Is the Key to Controlling HIV/AIDS","year":2025,"lang":"en","type":"review","venue":"Tropical Medicine and Infectious Disease","topic":"HIV/AIDS Research and Interventions","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"AIDS Vancouver; University of British Columbia","funders":"","keywords":"Pre-exposure prophylaxis; Treatment as prevention; Emtricitabine; Medicine; Human immunodeficiency virus (HIV); Transmission (telecommunications); Regimen; Tenofovir; Viral load; Antiretroviral therapy; Pill; Public health; Immunology; Men who have sex with men; Internal medicine; Pharmacology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002270357,0.0005228365,0.0008804641,0.0003975838,0.0008971906,0.002248811,0.001079732,0.00173191,0.01651372],"category_scores_gemma":[0.004486357,0.0002408398,0.0006220479,0.0004360868,0.001211236,0.001871511,0.002056977,0.004941625,0.005383511],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001387392,"about_ca_system_score_gemma":0.006484063,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006547641,"about_ca_topic_score_gemma":0.007433936,"domain_scores_codex":[0.998302,0.0005816377,0.00009981951,0.0002245468,0.0005791997,0.0002128119],"domain_scores_gemma":[0.9977196,0.0004579119,0.0002838148,0.0002420253,0.0006457319,0.0006509438],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002118919,0.0006657937,0.003002144,0.002177959,0.0001678756,0.0001963106,0.0004526002,0.0004144707,0.004078526,0.03832094,0.1538398,0.7964717],"study_design_scores_gemma":[0.00007666705,0.0005318125,0.006125111,0.002622537,0.0001711702,0.0006307708,0.0002702935,0.0003772529,0.00145508,0.01480942,0.9728908,0.00003901731],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"review","genre_scores_codex":[0.02981555,0.3449443,0.04037647,0.366962,0.01771025,0.001294439,0.002302459,0.001838047,0.1947564],"genre_scores_gemma":[0.2922964,0.3682811,0.06213286,0.1789383,0.01948745,0.0009960136,0.002821257,0.0004272308,0.07461941],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.01651372,"threshold_uncertainty_score":0.05524397,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03584306164746079,"score_gpt":0.3766480586225107,"score_spread":0.34080499697505,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}