{"id":"W4408387299","doi":"10.1016/j.cub.2025.02.008","title":"Cadherin 4 assembles a family of color-preferring retinal circuits that respond to light offset","year":2025,"lang":"en","type":"article","venue":"Current Biology","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre; Université de Montréal; Montreal Clinical Research Institute; McGill University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Consejo Nacional de Ciencia y Tecnología; Canada Research Chairs; Alfred P. Sloan Foundation","keywords":"Neuropil; Biology; Neuroscience; Neurite; Retinal; Inner plexiform layer; Retinal ganglion cell; Retina; Central nervous system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002217295,0.0004888568,0.000308779,0.0007731819,0.0003882282,0.0006779559,0.0005182175,0.0003206711,0.001478103],"category_scores_gemma":[0.0004235523,0.0003822467,0.0003055965,0.0002910172,0.0004045773,0.0005546744,0.0006340868,0.0005260284,0.0005779276],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008296794,"about_ca_system_score_gemma":0.0003106158,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001666597,"about_ca_topic_score_gemma":0.003333978,"domain_scores_codex":[0.9997429,0.0000322613,0.00001213355,0.00004384738,0.000102535,0.00006630969],"domain_scores_gemma":[0.999826,0.00001855644,0.0000462532,0.00001621435,0.00005344083,0.00003955464],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004988385,0.00001071018,0.001331031,0.00002521588,0.000009718465,0.00006606936,0.00002886998,0.0001941488,0.991763,0.0007688525,0.0002089861,0.005543578],"study_design_scores_gemma":[0.00001558922,0.000130257,0.02650038,0.00001182409,0.00003734732,0.0003945441,0.00012836,0.009675569,0.9540575,0.000575402,0.008452512,0.0000207325],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.976011,0.001775429,0.01629028,0.0001788539,0.00006389344,0.00004072772,0.0001494369,0.0003645726,0.005125769],"genre_scores_gemma":[0.9816571,0.0008235641,0.009561531,0.0001460409,0.00002201388,0.00002731975,0.0003317744,0.00006193513,0.007368634],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001666597,"threshold_uncertainty_score":0.006019771,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02981529003758206,"score_gpt":0.3227033108748983,"score_spread":0.2928880208373162,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}