{"id":"W4408388829","doi":"10.1016/j.clinbiochem.2025.110910","title":"The case of a bloody mess – Bictegravir/emtricitabine/tenofovir alafenamide induced colitis","year":2025,"lang":"en","type":"article","venue":"Clinical Biochemistry","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto","funders":"","keywords":"Emtricitabine; Tenofovir alafenamide; Medicine; Tenofovir; Bloody; Virology; Human immunodeficiency virus (HIV); Surgery; Antiretroviral therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007956186,0.0002525215,0.0002910028,0.00003032057,0.0002016488,0.00003684712,0.0005414857,0.0004923307,0.00001567126],"category_scores_gemma":[0.002279713,0.0002023205,0.000365085,0.0002114776,0.000520944,0.000003160173,0.0003551164,0.0002967869,0.00001019591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002862125,"about_ca_system_score_gemma":0.0009466691,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002160484,"about_ca_topic_score_gemma":0.00003980665,"domain_scores_codex":[0.9978225,0.000184209,0.0008948638,0.0005888342,0.0001257037,0.000383857],"domain_scores_gemma":[0.9977831,0.0002592581,0.0002598992,0.001200752,0.0002926058,0.0002044091],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002410235,0.001097213,0.0445544,0.0005267027,0.001133338,0.003189638,0.0000296944,0.000006939085,0.8956912,0.002148679,0.02405375,0.02515822],"study_design_scores_gemma":[0.00376056,0.0002469358,0.0672945,0.000139196,0.0003473609,0.0002539986,0.0004220138,0.00009995615,0.9141951,0.001240362,0.01131109,0.0006889447],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932538,0.000600363,0.00003555628,0.000325597,0.0003616983,0.000264834,0.00009545979,0.00002482844,0.005037925],"genre_scores_gemma":[0.9956875,0.0001444312,0.0001024937,0.0004160152,0.0002709898,0.00005447474,0.00008061489,0.00002289049,0.003220571],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02446928,"threshold_uncertainty_score":0.8250391,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01223601921598199,"score_gpt":0.3267243108431012,"score_spread":0.3144882916271192,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}