{"id":"W4408391075","doi":"10.1101/2025.03.11.641786","title":"Multimodal brain cell atlas across the adult macaque lifespan","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Research Foundation","funders":"","keywords":"Macaque; Atlas (anatomy); Neuroscience; Brain atlas; Brain Cell; Biology; Anatomy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003510476,0.0007075198,0.0004843584,0.00007229218,0.0003566981,0.0002538449,0.001240476,0.001117428,0.00001546813],"category_scores_gemma":[0.0002624584,0.0006305973,0.0003728127,0.0002475052,0.000248457,0.000007216554,0.0008340729,0.0009707694,0.0000353138],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008459388,"about_ca_system_score_gemma":0.0006870458,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003054946,"about_ca_topic_score_gemma":0.00006464941,"domain_scores_codex":[0.9968904,0.0002142716,0.0005533355,0.001265082,0.0002993765,0.0007775514],"domain_scores_gemma":[0.9970993,0.00006379911,0.0002938127,0.00179081,0.0005245721,0.0002276693],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00010863,0.0001896587,0.006533602,0.0003274588,0.0001665306,0.00001458727,0.00002760392,0.000214625,0.9893762,0.00008295584,0.002951307,0.000006772248],"study_design_scores_gemma":[0.0009417605,0.00009184224,0.007537137,0.0001683551,0.00008252294,2.218003e-8,0.000009622566,0.0005539829,0.9482849,0.000001334453,0.04150368,0.0008248026],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911087,0.0009856882,0.002929314,0.0009819634,0.001939998,0.0008386156,0.0009995548,0.0001409829,0.0000751509],"genre_scores_gemma":[0.9940576,0.0004702407,0.001707511,0.002077955,0.001153063,0.0001895356,0.000005471245,0.0001137899,0.0002248348],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04109132,"threshold_uncertainty_score":0.9996145,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008348299297018602,"score_gpt":0.2254947792562327,"score_spread":0.2171464799592141,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}