{"id":"W4408414304","doi":"10.1002/cmdc.202500059","title":"Boron in My Mind: A Comprehensive Review of the Evolution of the Diverse Syntheses of 4‐Borono‐ <scp>l</scp> ‐Phenylalanine, the Leading Agent for Boron Neutron Capture Therapy","year":2025,"lang":"en","type":"review","venue":"ChemMedChem","topic":"Boron Compounds in Chemistry","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Windsor Regional Hospital; University of Windsor","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Boron; Neutron capture; Cancer therapy; Radiation therapy; Scalability; Chemistry; Computer science; Nanotechnology; Combinatorial chemistry; Cancer; Medicine; Materials science; Organic chemistry; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006961275,0.0007115448,0.002958777,0.00008908598,0.00009856759,0.000008454837,0.001422041,0.0005646929,0.00002810531],"category_scores_gemma":[0.00259349,0.0003678192,0.001668119,0.0008175299,0.0006209872,0.00004865343,0.0004535038,0.0009558648,0.000001767613],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000944322,"about_ca_system_score_gemma":0.001445472,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001218012,"about_ca_topic_score_gemma":0.00002475274,"domain_scores_codex":[0.9963471,0.0003000235,0.001571105,0.0006263457,0.0006865471,0.0004688581],"domain_scores_gemma":[0.9920997,0.003185964,0.002052085,0.002009034,0.0005884908,0.00006471527],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008411492,0.0007517306,0.0003628155,0.7329899,0.001417965,0.000004259908,0.001446869,0.000006018347,0.01005541,0.0001541457,0.06194194,0.1907848],"study_design_scores_gemma":[0.0007692021,0.00006451611,0.0001921508,0.2757828,0.002121137,0.00002618388,0.00101115,0.00000711028,0.05458023,0.00002721747,0.665251,0.000167366],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001529242,0.9903799,0.000008684314,0.000447552,0.0004980192,0.004410095,0.0002631494,0.00001609055,0.002447235],"genre_scores_gemma":[0.005346813,0.9919695,0.0001532632,0.0002721423,0.0002173003,0.0004245866,0.00006910744,0.00007389475,0.001473375],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.603309,"threshold_uncertainty_score":0.9998774,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06561375964448668,"score_gpt":0.341579671121017,"score_spread":0.2759659114765303,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}