{"id":"W4408417662","doi":"10.3389/fimmu.2025.1545790","title":"Immunometabolic analysis of primary murine group 2 innate lymphoid cells: a robust step-by-step approach","year":2025,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital; McGill University Health Centre","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Canada Foundation for Innovation; Canadian Allergy, Asthma and Immunology Foundation","keywords":"Innate lymphoid cell; Biology; Effector; Phenotype; Crosstalk; Immune system; Innate immune system; Flow cytometry; Immunology; Acquired immune system; Computational biology; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006057783,0.0005006352,0.001928017,0.002513007,0.0001946224,0.00001714785,0.001023982,0.0008776076,0.0001064272],"category_scores_gemma":[0.00008465439,0.0005016405,0.0004156294,0.003331454,0.0009653688,0.0001715223,0.0004301344,0.0007026271,0.00003851975],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003244126,"about_ca_system_score_gemma":0.0002522774,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009209842,"about_ca_topic_score_gemma":0.0000554255,"domain_scores_codex":[0.9962887,0.0007197195,0.001140502,0.000829652,0.00007298075,0.0009484073],"domain_scores_gemma":[0.9982442,0.0001254356,0.0004193106,0.001048448,0.0001381056,0.00002451902],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00254088,0.00288266,0.05028983,0.0003682983,0.02449082,0.00001822245,0.001206825,0.0003782866,0.7658071,0.003668087,0.1178176,0.03053141],"study_design_scores_gemma":[0.01416847,0.0006301476,0.08735317,0.0001149496,0.003644671,0.00004724454,0.003922195,0.0008734366,0.06087651,0.0002055876,0.8266667,0.001496982],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5840942,0.1786511,0.1883527,0.0001201577,0.01089507,0.001382449,0.003932157,0.00030383,0.03226833],"genre_scores_gemma":[0.9311678,0.01508641,0.02800115,0.0008968209,0.00005290946,0.0003995213,0.006650558,0.0001214095,0.01762335],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.708849,"threshold_uncertainty_score":0.9997435,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006339467273352443,"score_gpt":0.1890937846082322,"score_spread":0.1827543173348798,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}