{"id":"W4408418475","doi":"10.1111/apt.70076","title":"Editorial: Upadacitinib—A Promising Induction Agent for Paediatric Crohn's Disease?","year":2025,"lang":"en","type":"editorial","venue":"Alimentary Pharmacology & Therapeutics","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; Western University","funders":"","keywords":"Medicine; Crohn disease; Crohn's disease; MEDLINE; Intensive care medicine; Disease; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003823374,0.004273336,0.003679271,0.002174263,0.001719976,0.003814441,0.004174125,0.01284908,0.009422706],"category_scores_gemma":[0.01167728,0.0009810976,0.002778309,0.0008678061,0.002130485,0.004568256,0.0007348285,0.01722521,0.008866548],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002032463,"about_ca_system_score_gemma":0.001392944,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009229467,"about_ca_topic_score_gemma":0.001204316,"domain_scores_codex":[0.9974565,0.0003873013,0.0003995973,0.0004631201,0.001083716,0.0002096875],"domain_scores_gemma":[0.9912186,0.004031379,0.0006478027,0.0002203836,0.002379999,0.001501759],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003119784,0.00004695965,0.0000944718,0.0006382877,0.00005016733,0.0007000859,0.00002226684,0.00009532487,0.0002163395,0.0003809126,0.9880811,0.009362139],"study_design_scores_gemma":[0.0003465005,0.0002925523,0.001134652,0.0008509799,0.00016535,0.002583137,0.00008252744,0.0005869205,0.0006273224,0.001240948,0.992029,0.00006010294],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.0003641499,0.008668394,0.0003344066,0.04414195,0.9439104,0.00006112643,0.0001791746,0.0001909781,0.002149515],"genre_scores_gemma":[0.001228901,0.003704465,0.0001219412,0.02253069,0.9680802,0.00002040621,0.00005837325,0.00003775879,0.004217381],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.01284908,"threshold_uncertainty_score":0.03152215,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0128011039362744,"score_gpt":0.3099830048250564,"score_spread":0.297181900888782,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}