{"id":"W4408446823","doi":"10.1016/j.cub.2025.02.032","title":"Diplonemid protists possess exotic endomembrane machinery, impacting models of membrane trafficking in modern and ancient eukaryotes","year":2025,"lang":"en","type":"article","venue":"Current Biology","topic":"Protist diversity and phylogeny","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Grantová Agentura České Republiky; Ministerstvo Školství, Mládeže a Tělovýchovy; Gordon and Betty Moore Foundation; University of Sydney; University of Alberta; Arizona State University","keywords":"Biology; Endomembrane system; Evolutionary biology; Cell biology; Endoplasmic reticulum","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002670929,0.0002734773,0.0002742577,0.0003211189,0.0009499088,0.001471408,0.0002256426,0.0007208858,0.0007895789],"category_scores_gemma":[0.0002579518,0.0001681976,0.0001802095,0.0003023922,0.001195166,0.001872081,0.0009531952,0.0007269869,0.0003190776],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008381603,"about_ca_system_score_gemma":0.0004375083,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005922844,"about_ca_topic_score_gemma":0.0009631357,"domain_scores_codex":[0.9999124,0.00001418933,0.00000890269,0.00002791743,0.00002125455,0.00001529851],"domain_scores_gemma":[0.9998475,0.00002331532,0.00004582273,0.00003176452,0.00001757616,0.00003408453],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005993554,0.00004543824,0.04450274,0.0005098886,0.00008907411,0.001625201,0.002391638,0.004159968,0.8024248,0.1082103,0.0006117426,0.03482984],"study_design_scores_gemma":[0.0001064779,0.00085182,0.3214224,0.0005162634,0.0003427153,0.01766806,0.01002398,0.04724871,0.246494,0.1421108,0.2129249,0.0002899693],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9827209,0.001426319,0.01057211,0.0006791231,0.00004466424,0.000005399266,0.0001468644,0.0001103521,0.004294346],"genre_scores_gemma":[0.9937703,0.001422163,0.003450402,0.0001107342,0.00001530255,0.000004228788,0.0001666731,0.00001331564,0.001046833],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001471408,"threshold_uncertainty_score":0.006081283,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02769281318629098,"score_gpt":0.2892708925261081,"score_spread":0.2615780793398171,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}