{"id":"W4408461773","doi":"10.3390/ijms26062610","title":"Evidence for Rab7b and Its Splice Isoforms Having Distinct Biological Functions from Rab7a","year":2025,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Rab; Biology; Gene isoform; Molecular biology; GTPase; splice; Mutant; Endosome; Cell biology; Biochemistry; Gene; Intracellular","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002124447,0.0002633864,0.0001739517,0.0003923293,0.0003079347,0.0003226687,0.0002549204,0.0005074987,0.001667577],"category_scores_gemma":[0.0002202027,0.0001777273,0.0003307585,0.000204827,0.0003474952,0.0002632654,0.0003780947,0.0004421214,0.0007068006],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002119852,"about_ca_system_score_gemma":0.0001502298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006997518,"about_ca_topic_score_gemma":0.0006900787,"domain_scores_codex":[0.9998176,0.00001643926,0.00001617335,0.00004364572,0.00007422447,0.0000319181],"domain_scores_gemma":[0.9997482,0.00004997784,0.0000412599,0.00004404417,0.00006951685,0.00004707313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001134783,0.00001509647,0.001493028,0.00005394145,0.00001289563,0.0002324581,0.00004041346,0.000008804432,0.9959919,0.0004195202,0.00005949845,0.001558924],"study_design_scores_gemma":[0.00007386685,0.0004542621,0.1682713,0.00005766203,0.0001349463,0.01894672,0.000547906,0.001282807,0.7895248,0.001565324,0.01910438,0.00003600793],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883367,0.004344449,0.002337855,0.0002782362,0.00003842379,0.00001350929,0.0003933998,0.00003738898,0.00421993],"genre_scores_gemma":[0.9894328,0.002214468,0.002782747,0.000230454,0.0000257593,0.00003360392,0.002658643,0.00003919756,0.00258233],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001667577,"threshold_uncertainty_score":0.005578637,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04444379805824598,"score_gpt":0.320426074521825,"score_spread":0.275982276463579,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}