{"id":"W4408461976","doi":"10.1016/j.semradonc.2025.01.001","title":"Principles and Paradigms of De-Escalated Elective Nodal Irradiation: Boldly Going Towards an Inflection Point in Head and Neck Radiotherapy","year":2025,"lang":"en","type":"review","venue":"Seminars in Radiation Oncology","topic":"Head and Neck Cancer Studies","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Inflection point; Head and neck; Radiation therapy; End point; Head (geology); Head and neck cancer; Medical physics; Nuclear medicine; Radiology; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007228004,0.0003040016,0.001975851,0.000850272,0.00005723957,0.00001133398,0.00006497744,0.0005829764,0.00001055273],"category_scores_gemma":[0.0003500293,0.0002927396,0.00008695439,0.00081432,0.0001194731,0.0001172695,0.00003226911,0.0005080356,3.813212e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001940688,"about_ca_system_score_gemma":0.001650651,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000253852,"about_ca_topic_score_gemma":0.0006444823,"domain_scores_codex":[0.9977917,0.0004249107,0.0008691877,0.0004738044,0.0001293015,0.000311089],"domain_scores_gemma":[0.9988352,0.0004422673,0.0003851115,0.0001747801,0.00005780876,0.0001048271],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002159097,0.0001813674,0.01226949,0.004103002,0.0001090523,0.00002786818,0.002775173,0.00001817479,0.000015621,0.0002391002,0.00008874965,0.9799565],"study_design_scores_gemma":[0.004375519,0.004108309,0.1384073,0.01783678,0.0003712527,0.0003271032,0.0001984927,0.00151995,0.00002292155,0.0001166282,0.8322883,0.0004274516],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02812578,0.9675274,0.00002381515,0.0003967037,0.0002059011,0.001196514,0.00001478978,0.00002828395,0.002480844],"genre_scores_gemma":[0.002985392,0.9951537,0.001131155,0.0001640276,0.0001312976,0.0002070832,0.00006384676,0.00002643859,0.0001370912],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.979529,"threshold_uncertainty_score":0.9999525,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03390225434460619,"score_gpt":0.4090397859793675,"score_spread":0.3751375316347613,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}