{"id":"W4408475496","doi":"10.1182/bloodadvances.2024014707","title":"Subgroup analysis of older patients ≥60 years with diffuse large B-cell lymphoma in the phase 3 POLARIX study","year":2025,"lang":"en","type":"article","venue":"Blood Advances","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Roche (Canada); Spinal Cord Injury BC; BC Cancer Agency","funders":"","keywords":"Medicine; Prednisone; Internal medicine; Rituximab; Vincristine; Hazard ratio; CHOP; Gastroenterology; Cyclophosphamide; Diffuse large B-cell lymphoma; Neutropenia; Lymphoma; Febrile neutropenia; Adverse effect; Confidence interval; Subgroup analysis; Surgery; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003022823,0.0008733319,0.002241793,0.0005146168,0.0002603969,0.0008098496,0.0004262268,0.0005974142,0.001538987],"category_scores_gemma":[0.002856637,0.000290105,0.005733707,0.0007890738,0.0001593869,0.0004234942,0.0005125959,0.0007241385,0.0001529651],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003532488,"about_ca_system_score_gemma":0.000437961,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001130393,"about_ca_topic_score_gemma":0.003237118,"domain_scores_codex":[0.9986688,0.0005880825,0.0001884969,0.0002696436,0.0001552893,0.0001297879],"domain_scores_gemma":[0.9988729,0.0004275562,0.0002931514,0.0002009824,0.00009634672,0.0001090249],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.3385904,0.00048371,0.5245611,0.002304047,0.08546801,0.0009834905,0.0003651447,0.001757228,0.006580383,0.0002287647,0.004207418,0.03447029],"study_design_scores_gemma":[0.04058744,0.009857384,0.8676986,0.0002897552,0.06840406,0.0008720559,0.0004414947,0.00289,0.001686001,0.000707707,0.006478044,0.00008744555],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863219,0.009827633,0.0004320877,0.0001318757,0.0001190967,0.0002474298,0.00224959,0.00001420682,0.0006561284],"genre_scores_gemma":[0.9956669,0.0008307741,0.0002122266,0.000182906,0.00009683179,0.0001969652,0.002509177,0.00001084813,0.0002934358],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003022823,"threshold_uncertainty_score":0.01598638,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004697327659869831,"score_gpt":0.2778089905230055,"score_spread":0.2731116628631357,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}