{"id":"W4408515489","doi":"10.1016/j.jri.2025.104520","title":"Inhibition of interleukin-1 signaling protects against Group B streptococcus-induced preterm birth and fetal loss in mice","year":2025,"lang":"en","type":"article","venue":"Journal of Reproductive Immunology","topic":"Neonatal and Maternal Infections","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Université de Montréal","funders":"National Health and Medical Research Council; Canadian Institutes of Health Research","keywords":"Interleukin 1β; Fetus; Streptococcus; Interleukin; Chemistry; Andrology; Immunology; Medicine; Biology; Pregnancy; Cytokine; Genetics; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003976813,0.0001194631,0.000409202,0.0005165192,0.00003292707,0.000007519932,0.00005477343,0.00009367051,0.000008413042],"category_scores_gemma":[0.0003108498,0.0000977084,0.00008748121,0.0002576613,0.0001597614,0.0001879563,0.00007373806,0.000433814,7.783145e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001304987,"about_ca_system_score_gemma":0.0001013531,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005943357,"about_ca_topic_score_gemma":0.00001234805,"domain_scores_codex":[0.9988738,0.0001041373,0.000555779,0.0002285879,0.00009503534,0.0001426552],"domain_scores_gemma":[0.9990432,0.0000518808,0.0004159879,0.0001586186,0.0003022368,0.00002811944],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001243675,0.0002262139,0.01270933,0.000179563,0.0002246612,0.0001433189,0.0004445203,0.000007048076,0.97182,0.0001642668,0.000005717707,0.01283167],"study_design_scores_gemma":[0.002259659,0.001376735,0.08312856,0.00108841,0.00004417078,0.0007966193,0.0004572534,0.000005640629,0.9091764,0.001367671,0.0002180024,0.00008087503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971783,0.0009457872,0.0002041368,0.0005870711,0.0003926982,0.0004236804,0.000003130113,0.000009738394,0.0002554829],"genre_scores_gemma":[0.9992816,0.000134082,0.0002800767,0.00004799401,0.0001078306,0.00001352811,0.000001788992,0.000008512298,0.0001245939],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07041923,"threshold_uncertainty_score":0.3984433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01054329891285512,"score_gpt":0.2646417756659255,"score_spread":0.2540984767530704,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}