{"id":"W4408530154","doi":"10.3390/ijms26062669","title":"Integrated Transcriptomic and Metabolomic Analysis Reveals Tissue-Specific Flavonoid Biosynthesis and MYB-Mediated Regulation of UGT71A1 in Panax quinquefolius","year":2025,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Ginseng Biological Effects and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Okanagan University College; University of British Columbia, Okanagan Campus; University of British Columbia","funders":"National Key Research and Development Program of China; National Natural Science Foundation of China","keywords":"Metabolomics; Flavonoid biosynthesis; MYB; Transcriptome; Tricin; KEGG; Biochemistry; Flavonoid; Biology; Metabolic pathway; Naringenin; Metabolome; Flavones; Chalcone synthase; Chemistry; Biosynthesis; Transcription factor; Metabolism; Gene expression; Enzyme; Botany; Gene; Bioinformatics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001619222,0.0004445305,0.0002977194,0.0003462964,0.0001829775,0.0002580032,0.0001512726,0.0002049258,0.000710734],"category_scores_gemma":[0.00008180847,0.0001428193,0.0004170209,0.0002394842,0.00009978367,0.0002390159,0.0002223048,0.0003022703,0.0001929109],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001923144,"about_ca_system_score_gemma":0.000139033,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001452408,"about_ca_topic_score_gemma":0.001546037,"domain_scores_codex":[0.9998838,0.000008395132,0.000005621725,0.00005934898,0.00002378899,0.00001899657],"domain_scores_gemma":[0.9999461,0.000007070403,0.00001621719,0.000004127387,0.00001481973,0.00001172311],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009352636,0.000008798108,0.001641879,0.00003687776,0.00001027312,0.00003812907,0.00002500568,0.00005364593,0.9961824,0.00003095703,0.00003752344,0.001840896],"study_design_scores_gemma":[0.00006319558,0.000703823,0.5641773,0.00002484422,0.0002008807,0.00104191,0.0003686104,0.0110417,0.4137216,0.0003103013,0.00830014,0.00004567914],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988023,0.001527911,0.005531405,0.00009788028,0.00002157027,0.0000399497,0.003911041,0.0001377577,0.0007094909],"genre_scores_gemma":[0.9846892,0.0007416194,0.005313324,0.0001312012,0.00001540712,0.00007039188,0.007013835,0.00004731425,0.001977711],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001452408,"threshold_uncertainty_score":0.002887845,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00943835248036409,"score_gpt":0.2755699184978339,"score_spread":0.2661315660174698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}