{"id":"W4408531199","doi":"10.1016/j.gimo.2025.102893","title":"P049: The long-chain fatty acid oxidation disorders (LC-FAOD) disease monitoring program: An evaluation of initial findings","year":2025,"lang":"en","type":"article","venue":"Genetics in Medicine Open","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Beta oxidation; Disease; Fatty acid; Chemistry; Medicine; Biochemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007325564,0.0003522344,0.0002989549,0.001436364,0.0007595504,0.000699023,0.0004647319,0.0005655211,0.002336822],"category_scores_gemma":[0.002419442,0.0001305188,0.0002852798,0.0009131925,0.0002314438,0.0005599153,0.0006020364,0.0004586798,0.0007183484],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006499215,"about_ca_system_score_gemma":0.0008044316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007110042,"about_ca_topic_score_gemma":0.004939958,"domain_scores_codex":[0.9995868,0.00009994397,0.0000583196,0.00007803579,0.0001115659,0.00006545772],"domain_scores_gemma":[0.9986581,0.0001582076,0.0002582857,0.00003514791,0.0005282316,0.0003620473],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000323295,0.0001477212,0.9803852,0.00003605135,0.00002172889,0.00283673,0.0001589177,0.00009520576,0.001592422,0.00005893402,0.00258295,0.01176074],"study_design_scores_gemma":[0.0000352407,0.0006102826,0.9858264,0.00006555805,0.00004647237,0.00758228,0.0004844893,0.00072879,0.001549717,0.00008528255,0.002971356,0.00001403967],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9849829,0.000512026,0.0008339775,0.001027065,0.00006078844,0.0003219679,0.003438741,0.00008515588,0.008737322],"genre_scores_gemma":[0.9921886,0.0003848193,0.002096845,0.0003144529,0.0000548113,0.0001717958,0.002755103,0.00003316639,0.002000411],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007110042,"threshold_uncertainty_score":0.01413727,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04011383171974348,"score_gpt":0.4156829463069461,"score_spread":0.3755691145872026,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}