{"id":"W4408536924","doi":"10.1007/s40744-025-00751-z","title":"A Response to: Letter to the Editor Regarding Impact of Race on the Efficacy and Safety of Tofacitinib in Rheumatoid Arthritis: Post Hoc Analysis of Pooled Clinical Trials","year":2025,"lang":"en","type":"letter","venue":"Rheumatology and Therapy","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Pfizer (Canada)","funders":"","keywords":"Tofacitinib; Post-hoc analysis; Rheumatoid arthritis; Post hoc; Medicine; Race (biology); Clinical trial; Internal medicine; Physical therapy; Gender studies; Sociology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01444039,0.001086286,0.004135686,0.001418233,0.002619128,0.004641579,0.00271503,0.03361733,0.006417753],"category_scores_gemma":[0.07380166,0.001001009,0.002545515,0.001803226,0.001877325,0.002462065,0.001071229,0.02673018,0.007578708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005919251,"about_ca_system_score_gemma":0.006576967,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004879947,"about_ca_topic_score_gemma":0.007471445,"domain_scores_codex":[0.9885247,0.004566486,0.002197351,0.00125504,0.002648225,0.0008081147],"domain_scores_gemma":[0.9464162,0.03428848,0.004379918,0.001421762,0.01017991,0.003313743],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004015037,0.00003966484,0.0006564267,0.0001537578,0.0001219557,0.000542682,0.00006106382,0.00005840108,0.0001227234,0.0003804447,0.9923093,0.005152074],"study_design_scores_gemma":[0.001849854,0.0004690492,0.006039422,0.001233929,0.0007602043,0.002311914,0.0005931809,0.001334941,0.0007611577,0.005863188,0.9785271,0.0002561508],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0004675802,0.001112977,0.0001247218,0.9383409,0.05857825,0.00003626081,0.0003932539,0.00004820252,0.0008978053],"genre_scores_gemma":[0.002852099,0.0006925837,0.0002806109,0.9236666,0.06953671,0.00007796788,0.00008543007,0.00004615155,0.002761812],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03361733,"threshold_uncertainty_score":0.07636899,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03474727501115461,"score_gpt":0.3772145317743655,"score_spread":0.3424672567632109,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}