{"id":"W4408543597","doi":"10.3390/ijms26062735","title":"A Metabolically Stable Apelin-13 Analog Acting as a Potent ITo Potassium Current Blocker with Potential Benefits for Brugada Syndrome","year":2025,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Apelin-related biomedical research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Pharmacology; Antagonist; Brugada syndrome; Potassium channel; Cardiac transient outward potassium current; Blockade; Chemistry; Patch clamp; Apelin; Medicine; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":{"n_in":0,"stratum":"aff_core","weight":5595.2375,"opus":{"tier":"OUT","genre":"empirical","about_ca":false,"confidence":"high","reason":"Pharmacology study of an apelin-13 analog as a potassium current blocker for Brugada syndrome."},"gpt":{"tier":"OUT","genre":"empirical","about_ca":false,"confidence":"high","reason":"It studies a potential cardiac drug analog for Brugada syndrome, not research practice."},"grok":{"tier":"OUT","genre":"empirical","about_ca":false,"confidence":"high","reason":"Patch-clamp pharmacology of an apelin analog on cardiac currents; biomedical physiology."}}}