{"id":"W4408574215","doi":"10.2139/ssrn.5177845","title":"Acute Presentations in Chemotherapy/Immune Checkpoint Inhibition in Neoadjuvant Triple Negative Breast Cancer: Experiences and Impact from Real-World Data","year":2025,"lang":"en","type":"preprint","venue":"SSRN Electronic Journal","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre","funders":"","keywords":"Triple-negative breast cancer; Breast cancer; Chemotherapy; Oncology; Medicine; Immune checkpoint; Immune system; Neoadjuvant therapy; Internal medicine; Cancer; Immunotherapy; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004148753,0.000200809,0.0003665513,0.0007518743,0.0007762038,0.001769186,0.000465139,0.0007787829,0.004366462],"category_scores_gemma":[0.02207686,0.000152923,0.0003337376,0.001800082,0.000828516,0.001458822,0.001901328,0.001026524,0.0006568707],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001262181,"about_ca_system_score_gemma":0.001289899,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003046616,"about_ca_topic_score_gemma":0.00367894,"domain_scores_codex":[0.9972083,0.001706292,0.0002573663,0.0002153101,0.0003231657,0.0002895751],"domain_scores_gemma":[0.9860576,0.007811538,0.002991119,0.0005882377,0.001094343,0.001457159],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003765285,0.001087977,0.7958405,0.0008720011,0.000168784,0.009976241,0.009118823,0.002058158,0.0009497284,0.002462636,0.02054832,0.1531515],"study_design_scores_gemma":[0.0005331446,0.00367427,0.7816153,0.002088404,0.0004539448,0.02574874,0.06656921,0.00555736,0.004520886,0.01459085,0.09434596,0.0003020061],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9806882,0.004307482,0.001575346,0.005097116,0.000139539,0.0001168116,0.002594177,0.00003395139,0.005447316],"genre_scores_gemma":[0.9893483,0.004233349,0.001331826,0.001069428,0.0002490187,0.00007066237,0.002622342,0.00004806189,0.001027169],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004366462,"threshold_uncertainty_score":0.02194095,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01417989435933329,"score_gpt":0.3314731598604061,"score_spread":0.3172932655010728,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}