{"id":"W4408576396","doi":"10.1111/hae.70017","title":"Perioperative Management With Efanesoctocog Alfa in Patients With Haemophilia A in the Phase 3 XTEND‐1 and XTEND‐Kids Studies","year":2025,"lang":"en","type":"article","venue":"Haemophilia","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; McMaster Children's Hospital","funders":"Swedish Orphan Biovitrum","keywords":"Medicine; Perioperative; Bleed; Haemophilia; Haemophilia A; Blood transfusion; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002158966,0.0002952176,0.0006262309,0.0001139878,0.0001547535,0.0006003559,0.0002369202,0.0002140424,0.0008880926],"category_scores_gemma":[0.001283967,0.0001144373,0.0008522772,0.0001591816,0.0002138447,0.0002714901,0.0002173288,0.0007126993,0.0001006936],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002896241,"about_ca_system_score_gemma":0.0007214266,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002084162,"about_ca_topic_score_gemma":0.0006358127,"domain_scores_codex":[0.9994198,0.0003459019,0.00006274353,0.00005428135,0.00007298143,0.00004421595],"domain_scores_gemma":[0.9989362,0.0003210704,0.0004803901,0.00006166815,0.00005930947,0.0001414021],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.2822104,0.008710273,0.290775,0.002908265,0.004456327,0.0007137054,0.0005082749,0.002179701,0.02039346,0.0004666424,0.003476901,0.3832011],"study_design_scores_gemma":[0.08392666,0.4858059,0.3860403,0.0008830979,0.004350447,0.003441001,0.000521117,0.002198196,0.01853844,0.0002886271,0.0139257,0.00008055945],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98754,0.01084894,0.0003302286,0.0001624225,0.00003295454,0.0001948209,0.00020798,0.000009778108,0.0006729595],"genre_scores_gemma":[0.9941884,0.003812871,0.000813056,0.0002218309,0.00005734041,0.0001803339,0.0005051168,0.000003342686,0.0002176956],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002158966,"threshold_uncertainty_score":0.01141787,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0199445065269588,"score_gpt":0.3500794133163287,"score_spread":0.33013490678937,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}