{"id":"W4408595874","doi":"10.1016/j.virol.2025.110510","title":"A strategy of enhancing the protective efficacy of seasonal influenza vaccines by providing additional immunity to neuraminidase and M2e","year":2025,"lang":"en","type":"article","venue":"Virology","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Division of Intramural Research, National Institute of Allergy and Infectious Diseases","keywords":"Neuraminidase; Biology; Virology; Immunity; Seasonal influenza; Immunology; Virus; Immune system; Medicine; Internal medicine; Coronavirus disease 2019 (COVID-19); Disease; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003785839,0.0005043597,0.0004287631,0.0002178549,0.0002209211,0.0004449501,0.0004713783,0.0006572088,0.002008345],"category_scores_gemma":[0.0002134791,0.00015674,0.0003612209,0.0001152652,0.0003087022,0.0005043705,0.0003529936,0.0009340958,0.0004535982],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003148679,"about_ca_system_score_gemma":0.000503878,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005200335,"about_ca_topic_score_gemma":0.0006558032,"domain_scores_codex":[0.9998573,0.00003350719,0.000009522337,0.00002873438,0.00002645999,0.00004439294],"domain_scores_gemma":[0.9999197,0.00001320855,0.00001470621,0.000016231,0.00001389405,0.00002234331],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004619512,0.0004773188,0.0002375031,0.00008736294,0.00002106055,0.00005595442,0.00001840169,0.0002902283,0.9864547,0.0009690507,0.0001915429,0.01073495],"study_design_scores_gemma":[0.0003626492,0.005481896,0.00252162,0.00002611108,0.00008602759,0.0005897781,0.00004640619,0.001995138,0.9792128,0.0005606505,0.009103316,0.00001364419],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.962722,0.00249508,0.0264426,0.001442073,0.0003254146,0.0004298235,0.000273094,0.0002043572,0.005665601],"genre_scores_gemma":[0.9737163,0.001315847,0.02022336,0.0005358888,0.00006645996,0.00012087,0.0001690883,0.00001477942,0.003837364],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002008345,"threshold_uncertainty_score":0.006718576,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03696507244539188,"score_gpt":0.3675777123615271,"score_spread":0.3306126399161352,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}