{"id":"W4408651881","doi":"10.1183/23120541.01298-2024","title":"A randomised controlled trial comparing epinephrine and dexamethasone to placebo in the treatment of infants with bronchiolitis: the Bronchiolitis in Infants Placebo <i>versus</i> Epinephrine and Dexamethasone (BIPED) study protocol","year":2025,"lang":"en","type":"article","venue":"ERJ Open Research","topic":"Respiratory viral infections research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Manitoba Health; University of Manitoba; University of Alberta; London Health Sciences Centre; Centre Hospitalier Universitaire Sainte-Justine; Children's Hospital of Winnipeg; Stollery Children's Hospital; University of Saskatchewan; Hospital for Sick Children; Public Health Ontario; University of Toronto; University of Calgary; Children's Hospital of Eastern Ontario; University of Ottawa","funders":"Perth Children's Hospital Foundation; National Health and Medical Research Council; Canadian Institutes of Health Research; Children's Hospital Research Institute of Manitoba; Research Manitoba; Western University; Starship Foundation; Alberta Children's Hospital Research Institute; CHEO Research Institute; Women and Children's Health Research Institute","keywords":"Medicine; Bronchiolitis; Dexamethasone; Placebo; Epinephrine; Randomized controlled trial; Anesthesia; Internal medicine; Pediatrics; Alternative medicine; Respiratory system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0115306,0.0004603298,0.001908408,0.001276337,0.0003888887,0.0003836467,0.0008036534,0.0001397814,0.0001083712],"category_scores_gemma":[0.005395863,0.00024941,0.00009571964,0.002671216,0.0006267698,0.0002751115,0.0007718093,0.001078982,0.000006919861],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004030088,"about_ca_system_score_gemma":0.0009441862,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01031632,"about_ca_topic_score_gemma":0.01782724,"domain_scores_codex":[0.990028,0.005347108,0.001277496,0.0009462096,0.001347025,0.001054147],"domain_scores_gemma":[0.9867339,0.01110052,0.0001809681,0.00127859,0.000413507,0.0002924759],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8942264,0.003361389,0.07637494,0.0001408634,0.0005004749,0.0001378958,0.002747162,0.00006557468,0.0003883529,0.0001826161,0.0001918681,0.02168249],"study_design_scores_gemma":[0.8174766,0.01536808,0.1592797,0.0004521034,0.00008556471,0.00002136922,0.002527103,0.0007855694,0.0004052025,0.00004272538,0.003348918,0.0002070504],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6702,0.000159689,0.00001178108,0.0007970328,0.00003498184,0.3160861,0.000006307318,0.00001351831,0.01269055],"genre_scores_gemma":[0.7018638,0.00008172009,0.0003118139,0.0001007859,0.00009005662,0.2968106,0.000004289641,0.00003172846,0.0007051764],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08290477,"threshold_uncertainty_score":0.9999958,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1285242534776969,"score_gpt":0.4742408758726729,"score_spread":0.3457166223949761,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}