{"id":"W4408651881","doi":"10.1183/23120541.01298-2024","title":"A randomised controlled trial comparing epinephrine and dexamethasone to placebo in the treatment of infants with bronchiolitis: the Bronchiolitis in Infants Placebo <i>versus</i> Epinephrine and Dexamethasone (BIPED) study protocol","year":2025,"lang":"en","type":"article","venue":"ERJ Open Research","topic":"Respiratory viral infections research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Manitoba Health; University of Manitoba; University of Alberta; London Health Sciences Centre; Centre Hospitalier Universitaire Sainte-Justine; Children's Hospital of Winnipeg; Stollery Children's Hospital; University of Saskatchewan; Hospital for Sick Children; Public Health Ontario; University of Toronto; University of Calgary; Children's Hospital of Eastern Ontario; University of Ottawa","funders":"Perth Children's Hospital Foundation; National Health and Medical Research Council; Canadian Institutes of Health Research; Children's Hospital Research Institute of Manitoba; Research Manitoba; Western University; Starship Foundation; Alberta Children's Hospital Research Institute; CHEO Research Institute; Women and Children's Health Research Institute","keywords":"Medicine; Bronchiolitis; Dexamethasone; Placebo; Epinephrine; Randomized controlled trial; Anesthesia; Internal medicine; Pediatrics; Alternative medicine; Respiratory system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007184452,0.003985188,0.008305462,0.000997046,0.0008607514,0.0020937,0.002338838,0.005289524,0.02015616],"category_scores_gemma":[0.01009118,0.001368116,0.003670948,0.0008851342,0.002298749,0.001683947,0.0009905357,0.00378023,0.002830851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001495124,"about_ca_system_score_gemma":0.004292078,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001403106,"about_ca_topic_score_gemma":0.002304701,"domain_scores_codex":[0.9941041,0.003613074,0.0005765642,0.000707531,0.0004368563,0.0005620301],"domain_scores_gemma":[0.9951627,0.001839612,0.001142913,0.0003186987,0.0005428998,0.0009931454],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9915726,0.002520359,0.0001111357,0.001581052,0.000543709,0.0000224527,0.00002214266,0.0001313019,0.0004641051,0.0001014562,0.0003358305,0.002593843],"study_design_scores_gemma":[0.9797485,0.01902041,0.0001927267,0.00006642694,0.0002281061,0.00000624057,0.000006137681,0.0001065017,0.00007189551,0.00008715251,0.0004580332,0.000007798845],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.3092946,0.008884111,0.003438021,0.002140062,0.005715422,0.6574529,0.006534031,0.0003863925,0.00615439],"genre_scores_gemma":[0.2965149,0.004395286,0.007866122,0.002319371,0.001645903,0.6773947,0.001873552,0.00003626482,0.007953856],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.02015616,"threshold_uncertainty_score":0.06742913,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1285242534776969,"score_gpt":0.4742408758726729,"score_spread":0.3457166223949761,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}