{"id":"W4408653578","doi":"10.1101/2025.03.14.643288","title":"The Neovaginal Microbiota, Symptoms, and Local Immune Correlates in Transfeminine Individuals with Penile Inversion Vaginoplasty","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's College Hospital; University of Toronto; Western University","funders":"","keywords":"Prevotella; Lactobacillus crispatus; Vaginoplasty; Medicine; Etiology; Immune system; Lactobacillus; Vagina; Immunology; Biology; Internal medicine; Surgery; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001300188,0.0001420031,0.000189929,0.0003977544,0.0004835639,0.0003742531,0.00008874695,0.0002762864,0.002003053],"category_scores_gemma":[0.0006146181,0.00009774932,0.0001333623,0.0003583432,0.0001736388,0.0001896028,0.000289103,0.0003048123,0.0001246303],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001249803,"about_ca_system_score_gemma":0.00008265039,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001055527,"about_ca_topic_score_gemma":0.001288792,"domain_scores_codex":[0.9999177,0.00001751201,0.000008230115,0.00002044671,0.00001828238,0.00001782086],"domain_scores_gemma":[0.9998136,0.00002575611,0.00008046776,0.00001050545,0.00002042429,0.00004925895],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003192378,0.0001177113,0.9850729,0.00003910904,0.00002446126,0.0005293152,0.0007726043,0.00001710629,0.00490747,0.00002199936,0.0001138762,0.008064253],"study_design_scores_gemma":[0.000005786821,0.0004565785,0.995423,0.00002035584,0.00002305904,0.00179816,0.001458187,0.00006297944,0.0004284942,0.0000334063,0.000285025,0.000004981193],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996102,0.0001215125,0.00003817957,0.00001872154,0.000002027815,0.000004134075,0.00004984558,0.000001147543,0.0001542208],"genre_scores_gemma":[0.9995824,0.00007541429,0.00008093134,0.00002885712,0.000003494469,0.000005051565,0.00005946029,8.406311e-7,0.000163555],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002003053,"threshold_uncertainty_score":0.006700873,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006550213793372212,"score_gpt":0.217823485591103,"score_spread":0.2112732717977308,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}