{"id":"W4408721380","doi":"10.21203/rs.3.rs-6087158/v1","title":"Neotenic expansion of adult-born dentate granule cells reconfigures GABAergic inhibition to enhance social memory consolidation","year":2025,"lang":"en","type":"preprint","venue":"Research Square","topic":"Memory and Neural Mechanisms","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Kootenay Association for Science & Technology","funders":"","keywords":"Neuroscience; Memory consolidation; Hippocampal formation; Dentate gyrus; Inhibitory postsynaptic potential; Parvalbumin; Excitatory postsynaptic potential; Neurogenesis; Synaptic plasticity; Biology; Psychology; Hippocampus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001328314,0.0004181136,0.0005690134,0.0003046403,0.0001221624,0.0006850815,0.000680036,0.0004610904,0.001930342],"category_scores_gemma":[0.0002112703,0.0001773985,0.000296746,0.0001508124,0.0005322187,0.0004479382,0.0006341886,0.001991221,0.000460849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000400287,"about_ca_system_score_gemma":0.0003920603,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005642919,"about_ca_topic_score_gemma":0.001889558,"domain_scores_codex":[0.9998497,0.000005199312,0.000009251095,0.00004787705,0.00003633343,0.00005152933],"domain_scores_gemma":[0.9997454,0.00002600798,0.00005929455,0.00003460491,0.00002311262,0.000111487],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004104493,0.0001873911,0.0006628518,0.00007020138,0.00002015718,0.0002482201,0.0000729096,0.0003282527,0.9830655,0.0005725437,0.0002720742,0.01408955],"study_design_scores_gemma":[0.0001981789,0.0009294308,0.01098689,0.00003269396,0.0001018305,0.000418195,0.0002452578,0.002722729,0.9792053,0.0007276047,0.004413622,0.00001832664],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949243,0.0004508185,0.002421506,0.0001278971,0.0001526002,0.00001644815,0.0002069514,0.0001727708,0.001526583],"genre_scores_gemma":[0.9947757,0.0004036964,0.001320449,0.0001076444,0.00002410964,0.00002390993,0.0001908515,0.0001030778,0.003050667],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001930342,"threshold_uncertainty_score":0.006457686,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1018410480051035,"score_gpt":0.4257014469900964,"score_spread":0.323860398984993,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}