{"id":"W4408725747","doi":"10.1038/s41598-025-94666-y","title":"Tryptic oncopeptide secreted from the gut bacterium Cronobacter malonaticus PO3 promotes colorectal cancer","year":2025,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Enterobacteriaceae and Cronobacter Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Colorectal cancer; Cell growth; Cancer research; Dysplasia; In vivo; Biology; Cancer; Molecular biology; Medicine; Pathology; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006231954,0.0002630918,0.0001534356,0.0001765107,0.0001002837,0.000193835,0.00007164583,0.0002458587,0.0005482668],"category_scores_gemma":[0.0001477873,0.00006194384,0.0001749345,0.0001210807,0.0001467039,0.0001267674,0.0001828531,0.0002452932,0.000170769],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009190735,"about_ca_system_score_gemma":0.00010171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004180814,"about_ca_topic_score_gemma":0.0004380055,"domain_scores_codex":[0.9999378,0.00001100408,0.000005741017,0.00001160089,0.00001565699,0.00001827553],"domain_scores_gemma":[0.9999031,0.0000144616,0.00003456007,0.00000745145,0.00001055155,0.0000297898],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001099844,0.00001442029,0.001582885,0.00001805609,0.000003076274,0.0002029848,0.000009554217,0.00001770907,0.9969958,0.00000831568,0.00001093946,0.001026317],"study_design_scores_gemma":[0.00002113517,0.001086314,0.1515613,0.00001523236,0.00003752182,0.003728932,0.0002109605,0.0007602343,0.8405921,0.00004991355,0.001928716,0.000007577776],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985251,0.0004847498,0.0005095783,0.00005524469,0.000009543591,0.00001123901,0.00008844837,0.00001051884,0.0003056716],"genre_scores_gemma":[0.9982539,0.0003239466,0.0008186562,0.00004356226,0.000007036232,0.000005905831,0.0001836668,0.000003749835,0.0003596523],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005482668,"threshold_uncertainty_score":0.001834154,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008822842622897188,"score_gpt":0.275128243805847,"score_spread":0.2663054011829498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}