{"id":"W4408743496","doi":"10.1016/j.reval.2025.104319","title":"Impact of atopic status, prior omalizumab use and baseline blood eosinophil count alone and in combination with total serum IgE on maintenance OCS reduction outcomes in patients with severe asthma treated with mepolizumab in the REALITI-A study","year":2025,"lang":"en","type":"article","venue":"Revue française d'allergologie","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital","funders":"","keywords":"Omalizumab; Medicine; Asthma; Eosinophil; Immunoglobulin E; Immunology; Baseline (sea); Internal medicine; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001958206,0.0002986017,0.0006295225,0.0003390553,0.00006411974,0.00002228802,0.00006920207,0.0001040982,0.000004790285],"category_scores_gemma":[0.0001818164,0.0001611241,0.00003488269,0.0005644778,0.0001626914,0.0001716144,0.00003060172,0.0002548208,2.013194e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001838607,"about_ca_system_score_gemma":0.0002737512,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003190358,"about_ca_topic_score_gemma":0.003317541,"domain_scores_codex":[0.9982793,0.0002585863,0.0004169614,0.0004395096,0.0002787431,0.0003269202],"domain_scores_gemma":[0.9990223,0.0001866289,0.0001701348,0.0003737172,0.0001705094,0.00007669044],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00729518,0.004056508,0.9845819,0.0001699326,0.0001378248,0.0003143451,0.001356291,0.0003210779,0.000008603748,0.00001824843,0.00001223295,0.001727863],"study_design_scores_gemma":[0.02566798,0.008665109,0.9632396,0.0009035137,0.0001108183,0.00004669362,0.001086902,0.00007373602,0.00001540989,0.000005253033,0.00001017751,0.0001748531],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973933,0.0001980737,0.000002965717,0.0002847394,0.0000178332,0.001960068,0.00008985367,0.00002541952,0.00002772827],"genre_scores_gemma":[0.9995943,0.00007268304,0.00005531302,0.00004206669,0.000009455611,0.00007640247,0.00006441003,0.00002082449,0.00006459456],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02134234,"threshold_uncertainty_score":0.6570452,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01096370869031942,"score_gpt":0.2528340615818644,"score_spread":0.241870352891545,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}