{"id":"W4408763596","doi":"10.1002/btm2.10736","title":"Key parameters for designing robust <scp>2D</scp> and <scp>3D</scp> spheroid models for <i>in vitro</i> atherosclerosis research","year":2025,"lang":"en","type":"review","venue":"Bioengineering & Translational Medicine","topic":"Coronary Interventions and Diagnostics","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital; McGill University","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Key (lock); In vitro; Computer science; Cell biology; Chemistry; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001508979,0.0006562736,0.001954766,0.001017147,0.0001834458,0.00004479277,0.0002595329,0.0005015657,0.000006989333],"category_scores_gemma":[0.002567736,0.0005802692,0.0005645631,0.0008555999,0.0002106507,0.0001284902,0.00004231052,0.0006965126,0.000002631872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002077878,"about_ca_system_score_gemma":0.0004158416,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004350605,"about_ca_topic_score_gemma":0.000009952606,"domain_scores_codex":[0.9963599,0.0001041363,0.001245876,0.0008311351,0.0006353926,0.0008235881],"domain_scores_gemma":[0.9867322,0.01206163,0.0001713987,0.0003966937,0.000365251,0.0002728088],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000139201,0.0008529617,0.00006842001,0.1664444,0.001716985,0.00004579456,0.001736728,0.02363591,0.001212833,0.003724608,0.01386065,0.7865615],"study_design_scores_gemma":[0.007158857,0.001661179,0.0001152186,0.1111226,0.003416094,0.00007754879,0.0003599137,0.06177342,0.0001562259,0.0009312727,0.8129243,0.0003032995],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001148106,0.7201132,0.2749774,0.0002523228,0.0003644308,0.003507394,0.0003973397,0.00008689524,0.0001862186],"genre_scores_gemma":[0.000674368,0.9050066,0.08802209,0.00008988829,0.0005136837,0.002413692,0.001651713,0.0001875159,0.001440393],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7990637,"threshold_uncertainty_score":0.9996649,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1561924714002073,"score_gpt":0.3626277941906048,"score_spread":0.2064353227903975,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}