{"id":"W4408763596","doi":"10.1002/btm2.10736","title":"Key parameters for designing robust <scp>2D</scp> and <scp>3D</scp> spheroid models for <i>in vitro</i> atherosclerosis research","year":2025,"lang":"en","type":"review","venue":"Bioengineering & Translational Medicine","topic":"Coronary Interventions and Diagnostics","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital; McGill University","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Key (lock); In vitro; Computer science; Cell biology; Chemistry; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001291317,0.0008885603,0.001180252,0.00150774,0.0002329237,0.001016329,0.0007577513,0.0009545744,0.003032227],"category_scores_gemma":[0.001263079,0.0003847397,0.0007234856,0.0009906046,0.0003715174,0.001288451,0.0005807597,0.001182044,0.001829066],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004816986,"about_ca_system_score_gemma":0.001105616,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008418702,"about_ca_topic_score_gemma":0.001171548,"domain_scores_codex":[0.999566,0.0001107787,0.00006567753,0.00005780543,0.0001627282,0.00003702032],"domain_scores_gemma":[0.9995705,0.0001713925,0.00008466174,0.00002206218,0.0001298148,0.00002166403],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00022449,0.000234716,0.0004785047,0.07110403,0.0001768377,0.000450218,0.0002163949,0.005229266,0.1395789,0.02153737,0.01867589,0.7420934],"study_design_scores_gemma":[0.00005531412,0.0006192675,0.001638902,0.007039604,0.0005406424,0.001091545,0.0001727942,0.002216496,0.06223649,0.004992313,0.9192837,0.0001129415],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004530269,0.9735197,0.01329091,0.0007652863,0.0004057964,0.000195165,0.0003755757,0.0001170134,0.006800164],"genre_scores_gemma":[0.02599656,0.9554223,0.01495752,0.0003988419,0.0001513308,0.0002981007,0.0005445312,0.00003560142,0.00219523],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003032227,"threshold_uncertainty_score":0.01014382,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1561924714002073,"score_gpt":0.3626277941906048,"score_spread":0.2064353227903975,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}