{"id":"W4408772221","doi":"10.1002/mnfr.70044","title":"Prenatal Intake of High Multivitamins or Folic Acid With or Without Choline Contributes to Gut Microbiota‐Associated Dysregulation of Serotonin in Offspring","year":2025,"lang":"en","type":"article","venue":"Molecular Nutrition & Food Research","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Offspring; Endocrinology; Serotonergic; Internal medicine; Serotonin; Gut flora; Micronutrient; Physiology; Choline; Biology; Gut–brain axis; Medicine; Pregnancy; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001055632,0.0003081541,0.0003203172,0.0002682029,0.0002068713,0.0002696953,0.0001507143,0.00028852,0.001392945],"category_scores_gemma":[0.0002568923,0.0001864196,0.000206685,0.0001203081,0.0002346509,0.0001156056,0.000288779,0.0006918082,0.0001392999],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003246685,"about_ca_system_score_gemma":0.0003009886,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004133664,"about_ca_topic_score_gemma":0.007654881,"domain_scores_codex":[0.9998102,0.00002693458,0.00001120547,0.00007181575,0.00004081104,0.00003918524],"domain_scores_gemma":[0.9998065,0.00001401683,0.00008267441,0.00001355943,0.00002099743,0.00006225945],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002250014,0.0002047319,0.06458326,0.0002199052,0.0001285424,0.0005936644,0.000233712,0.00006246543,0.9202734,0.0001431129,0.0003164982,0.01099062],"study_design_scores_gemma":[0.00003337054,0.00129106,0.8602458,0.00007293934,0.0002613823,0.0008911137,0.0005063054,0.0004705892,0.1332511,0.0002411303,0.00270817,0.00002714587],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972858,0.001135416,0.0006239786,0.0001062636,0.00001553042,0.000007413032,0.0004404551,0.00003191617,0.0003532601],"genre_scores_gemma":[0.9958768,0.0008983954,0.0008898345,0.0001290458,0.000007305927,0.00003280215,0.0003379905,0.00002009102,0.001807731],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004133664,"threshold_uncertainty_score":0.008219242,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02529286725948606,"score_gpt":0.3456399537474358,"score_spread":0.3203470864879497,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}