{"id":"W4408773535","doi":"10.1016/j.bioactmat.2025.03.004","title":"Minimally invasive snakebite inspired microneedle delivery system for internal organs","year":2025,"lang":"en","type":"article","venue":"Bioactive Materials","topic":"Advancements in Transdermal Drug Delivery","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Cancer Institute; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Biomedical engineering; Delivery system; Materials science; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001280219,0.0002161923,0.000185271,0.0001942369,0.0001608679,0.0002250922,0.0001660079,0.0004943353,0.0005816788],"category_scores_gemma":[0.0001216069,0.0001141322,0.0002970409,0.00006705681,0.000194148,0.0002921615,0.000276297,0.0003093799,0.0002340108],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001966621,"about_ca_system_score_gemma":0.0001757146,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001946843,"about_ca_topic_score_gemma":0.0002596368,"domain_scores_codex":[0.9999168,0.00001011892,0.000007160854,0.00001953458,0.00003594122,0.00001040002],"domain_scores_gemma":[0.9999406,0.000009688774,0.00001930698,0.000006662217,0.00001264392,0.0000111196],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001573528,0.000008436815,0.0001538401,0.00009437361,0.000005208569,0.00007747594,0.00002569762,0.0002103387,0.9931037,0.0002472088,0.00008506096,0.005972921],"study_design_scores_gemma":[0.0000117924,0.000299872,0.002435864,0.00002032995,0.00002819196,0.001045292,0.00002654316,0.003870297,0.9799786,0.0001385889,0.01212213,0.00002250906],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7671461,0.006897894,0.2189514,0.0005791873,0.0001976364,0.0002547121,0.0002252871,0.0009857035,0.004762024],"genre_scores_gemma":[0.9178128,0.002326797,0.07390036,0.0003021449,0.00002561647,0.0001190315,0.0001712301,0.00004582239,0.005296176],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005816788,"threshold_uncertainty_score":0.001945913,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06253601041870599,"score_gpt":0.3894658846230027,"score_spread":0.3269298742042967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}