{"id":"W4408796111","doi":"10.1016/j.labinv.2024.102888","title":"657 Comparing the Prognostic Significance of Pre- Versus Post-Treatment Histologic Grade in Esophageal Adenocarcinomas Undergoing Neoadjuvant Chemoradiation","year":2025,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Esophageal Cancer Research and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto General Hospital; University Health Network; University of Toronto","funders":"","keywords":"Medicine; Neoadjuvant therapy; Esophageal cancer; Esophageal adenocarcinoma; Internal medicine; Adenocarcinoma; Chemoradiotherapy; Oncology; Chemotherapy; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005010315,0.0001658511,0.0002656861,0.0004765408,0.0002111269,0.0006150802,0.0002025724,0.0003323251,0.00111825],"category_scores_gemma":[0.001719358,0.00009547945,0.0003116291,0.0005021919,0.000259516,0.000295495,0.0002295573,0.0003009478,0.0002105998],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002944329,"about_ca_system_score_gemma":0.0002561329,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001025303,"about_ca_topic_score_gemma":0.002192478,"domain_scores_codex":[0.9997386,0.00008681349,0.00002840919,0.00003449966,0.00004159692,0.00007011287],"domain_scores_gemma":[0.9990659,0.0003408219,0.0002126003,0.0000632335,0.000108856,0.000208568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002443904,0.00004745154,0.9909304,0.00001286472,0.00005998785,0.00009901064,0.00003864809,0.00006738379,0.001842874,0.00002566964,0.00005397787,0.004377882],"study_design_scores_gemma":[0.00002417874,0.0006438327,0.9971702,0.00000604785,0.00009596441,0.0002942499,0.0001931633,0.0003572403,0.0008705213,0.0000468327,0.0002931908,0.000004641786],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991313,0.0003181094,0.00005707255,0.00002313329,0.000007633557,0.000002714974,0.00005385212,0.000001782736,0.0004045086],"genre_scores_gemma":[0.9995348,0.00008348493,0.00005218319,0.00001534297,0.00001166973,0.000002477236,0.0001433693,0.000001096287,0.0001555598],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00111825,"threshold_uncertainty_score":0.003740907,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0344583396992236,"score_gpt":0.3056432887737277,"score_spread":0.2711849490745041,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}