{"id":"W4408796455","doi":"10.1016/j.labinv.2024.102511","title":"286 Phosphodiesterase Genes in Cardiac Myxoma Pathogenesis","year":2025,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Pathogenesis; Myxoma; Phosphodiesterase; Gene; Medicine; Biology; Pathology; Internal medicine; Bioinformatics; Genetics; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002305874,0.0002276742,0.0001401202,0.0006101342,0.0001404465,0.0002904146,0.0001714003,0.0003270173,0.001215468],"category_scores_gemma":[0.0003584339,0.0001236436,0.00010928,0.0002106738,0.0002984785,0.0001438321,0.0001485478,0.0003262329,0.0001732198],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001566531,"about_ca_system_score_gemma":0.0001292407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002769162,"about_ca_topic_score_gemma":0.0002329057,"domain_scores_codex":[0.9998815,0.0000325332,0.00001250618,0.00002125024,0.00003041078,0.00002174455],"domain_scores_gemma":[0.9998378,0.00005653027,0.0000402109,0.00001070279,0.00002169691,0.00003311389],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002203262,0.0002411127,0.09908374,0.0001326338,0.00003310679,0.005308295,0.0001940413,0.0003464762,0.8573608,0.001305286,0.0003258962,0.03346537],"study_design_scores_gemma":[0.0001679176,0.000986321,0.6219775,0.00008187567,0.0001236142,0.01281283,0.0006568442,0.003332757,0.3501187,0.001675614,0.008047124,0.00001891405],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928888,0.002257529,0.001389599,0.0002892163,0.00002408905,0.00002397995,0.0001685126,0.00001842823,0.002939724],"genre_scores_gemma":[0.9960574,0.0008881541,0.00151587,0.00009388412,0.00002540485,0.00001203758,0.0001265635,0.000003880393,0.001276804],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001215468,"threshold_uncertainty_score":0.00406611,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009165840535009405,"score_gpt":0.2566343069140014,"score_spread":0.2474684663789919,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}