{"id":"W4408797869","doi":"10.1016/j.labinv.2024.102393","title":"169 T-box Transcription Factor 21 (T-bet/TBX21) Influences Transcriptional Activity Pathways and Immune-specific Genes in Breast Cancers","year":2025,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Transcription factor; Immune system; Gene; Cancer research; Biology; Transcription (linguistics); Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000160344,0.0002008951,0.0001670389,0.0001533924,0.0001179966,0.00004987447,0.00009653398,0.0002697818,0.00001825764],"category_scores_gemma":[0.0000131229,0.0002256722,0.00004800099,0.0004578146,0.0002142376,0.00005313222,0.0000155452,0.0001456316,0.000001697716],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001857272,"about_ca_system_score_gemma":0.0004703246,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001456709,"about_ca_topic_score_gemma":0.0004498815,"domain_scores_codex":[0.9987714,0.0001330868,0.000292868,0.0004368827,0.0001665609,0.0001992237],"domain_scores_gemma":[0.9994469,0.00001094324,0.0001065842,0.0002121925,0.0001502039,0.00007320735],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001164733,0.00001827431,0.01364682,0.000040307,0.00002988018,4.794621e-7,0.0002246046,0.001318935,0.9777602,0.0004811192,0.0001187711,0.006244153],"study_design_scores_gemma":[0.0006924151,0.00004615933,0.4078704,0.00007297542,0.00001518152,0.000002380417,0.00009385819,0.0003589366,0.5857434,0.0003609353,0.004534279,0.0002091297],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918355,0.00601111,0.0005738867,0.0005864509,0.0003997469,0.000287785,0.0002139934,0.00002981372,0.00006174276],"genre_scores_gemma":[0.9981734,0.001005941,0.0001813295,0.0001645153,0.0001345498,0.0000678683,0.0002076404,0.00001589264,0.00004884792],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3942235,"threshold_uncertainty_score":0.9202644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01161338925139448,"score_gpt":0.2250300852854856,"score_spread":0.2134166960340911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}