{"id":"W4408808337","doi":"10.3390/pharmaceutics17040411","title":"Pharmacokinetics of Psilocybin: A Systematic Review","year":2025,"lang":"en","type":"review","venue":"Pharmaceutics","topic":"Psychedelics and Drug Studies","field":"Psychology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal Ottawa Mental Health Centre; University of Toronto; Centre for Addiction and Mental Health; University of Ottawa; Women and Children’s Health Research Institute; University of Alberta; Western University; St. Michael's Hospital","funders":"","keywords":"Psilocybin; Pharmacokinetics; Pharmacology; Metabolite; Bioavailability; Active metabolite; Hallucinogen; Chemistry; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008619489,0.0007094824,0.005399075,0.0003093834,0.00006304456,0.00001406255,0.000910933,0.0002481149,0.0005327101],"category_scores_gemma":[0.0002251354,0.0005526282,0.001096205,0.0009852609,0.0001120563,0.00002092642,0.0002630886,0.0006344778,0.0004206845],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000734315,"about_ca_system_score_gemma":0.0001968486,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004082215,"about_ca_topic_score_gemma":4.343409e-7,"domain_scores_codex":[0.9957669,0.0006803998,0.002159353,0.0005435274,0.000364893,0.0004848847],"domain_scores_gemma":[0.9964002,0.0009181338,0.001289924,0.001046872,0.0002165415,0.0001282682],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000002559272,0.0001535627,2.373346e-7,0.8608847,0.001882594,0.00001556367,0.00007057143,5.273866e-8,6.450625e-8,0.0009757721,0.03359954,0.1024147],"study_design_scores_gemma":[0.0001614754,0.00001057601,1.651256e-8,0.4432397,0.01592644,0.00002031827,0.00001197992,0.000001588307,5.752694e-7,0.00001474106,0.5403748,0.0002378636],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[1.920921e-8,0.9518917,0.00004192231,0.00008342567,0.002406869,0.003812958,0.0002937424,0.00007528967,0.04139409],"genre_scores_gemma":[0.000001061384,0.9914857,0.00005418366,0.00104821,0.0001465721,0.0009493398,0.00005525462,0.00006829284,0.00619135],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5067752,"threshold_uncertainty_score":0.9996925,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1793171438652026,"score_gpt":0.534024299745558,"score_spread":0.3547071558803554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}