{"id":"W4408808337","doi":"10.3390/pharmaceutics17040411","title":"Pharmacokinetics of Psilocybin: A Systematic Review","year":2025,"lang":"en","type":"review","venue":"Pharmaceutics","topic":"Psychedelics and Drug Studies","field":"Psychology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal Ottawa Mental Health Centre; University of Toronto; Centre for Addiction and Mental Health; University of Ottawa; Women and Children’s Health Research Institute; University of Alberta; Western University; St. Michael's Hospital","funders":"","keywords":"Psilocybin; Pharmacokinetics; Pharmacology; Metabolite; Bioavailability; Active metabolite; Hallucinogen; Chemistry; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003562514,0.001316093,0.006120988,0.007044537,0.0004321552,0.001856357,0.00161964,0.001393619,0.005790946],"category_scores_gemma":[0.01380815,0.0007690379,0.00658559,0.008954109,0.0006346787,0.001651774,0.0009189546,0.000807766,0.0004400986],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002370359,"about_ca_system_score_gemma":0.007956683,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007115551,"about_ca_topic_score_gemma":0.01707355,"domain_scores_codex":[0.9973069,0.0007562264,0.001042332,0.0002809206,0.0005166462,0.00009690096],"domain_scores_gemma":[0.9879115,0.008023601,0.002600087,0.0001582959,0.001170714,0.0001358955],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0002333786,0.00001299507,0.0004860335,0.9653588,0.005698058,0.0001061098,0.00007844844,0.00008880147,0.000182033,0.0000926116,0.001051634,0.02661104],"study_design_scores_gemma":[0.0004500542,0.0005314405,0.007497754,0.8406102,0.1169967,0.0009586496,0.0003333198,0.0001784568,0.0003841448,0.0002896827,0.0317082,0.00006134623],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008984759,0.9980782,0.00009567879,0.0001347685,0.0000393713,0.0001238379,0.0004200957,0.000006053034,0.0002033578],"genre_scores_gemma":[0.01085205,0.9878849,0.0003606039,0.0002782082,0.0000484255,0.000206282,0.0002581532,0.00000481275,0.0001065732],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.007115551,"threshold_uncertainty_score":0.01937264,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1793171438652026,"score_gpt":0.534024299745558,"score_spread":0.3547071558803554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}