{"id":"W4408818161","doi":"10.1002/aoc.70020","title":"A New Trend to Introduce a Biocompatible Drug Carrier Based on Immunoglobulin for Prolonged Release of Palladium (II) Complex as an Anticancer Agent: Drug Release and Cytotoxicity Assessment","year":2025,"lang":"en","type":"article","venue":"Applied Organometallic Chemistry","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Shahid Beheshti University of Medical Sciences","keywords":"Chemistry; Nanocarriers; Carboplatin; Cytotoxicity; In vivo; MTT assay; Drug carrier; Controlled release; Cisplatin; Pharmacology; Apoptosis; Biophysics; Drug delivery; Biochemistry; In vitro; Chemotherapy; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000554412,0.0004244114,0.0006666366,0.0001314349,0.0002662253,0.0001086998,0.0005380507,0.0001018472,0.001262378],"category_scores_gemma":[0.0001161539,0.0004260893,0.0001053153,0.0007218893,0.0001847816,0.00009423616,0.0002349597,0.0001815597,0.00001638458],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002900208,"about_ca_system_score_gemma":0.0007606524,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000256385,"about_ca_topic_score_gemma":0.00004083444,"domain_scores_codex":[0.9971986,0.00006227625,0.0006673924,0.001060379,0.0004503145,0.0005610529],"domain_scores_gemma":[0.9979218,0.0001841888,0.0002585834,0.001062197,0.0001117344,0.0004614483],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001195864,0.0006045928,0.0001599815,0.0003572208,0.00004725987,0.000004126731,0.0003125211,0.0006760366,0.9941983,0.0003059039,0.001380403,0.0007578169],"study_design_scores_gemma":[0.002974546,0.0001309512,0.001249539,0.00008213014,0.0001415349,0.000001302679,0.0001898439,0.001498427,0.9920191,0.0002383236,0.00107127,0.0004030997],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953218,0.00007699035,0.0009294277,0.00109311,0.00008188864,0.00137623,0.0003018186,0.0001234387,0.0006953599],"genre_scores_gemma":[0.9887345,0.00000631342,0.009122296,0.0008054916,0.0001107961,0.0003023929,0.0001355065,0.00004810682,0.0007346157],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008192869,"threshold_uncertainty_score":0.9998191,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009699131840166601,"score_gpt":0.2611629948601215,"score_spread":0.2514638630199549,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}