{"id":"W4408826168","doi":"10.1371/journal.ppat.1012964","title":"Dissecting transmission to understand parasite evolution","year":2025,"lang":"en","type":"review","venue":"PLoS Pathogens","topic":"Evolution and Genetic Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canada Excellence Research Chairs, Government of Canada; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Virulence; Transmission (telecommunications); Parasite hosting; Abiotic component; Host (biology); Biology; Effector; Evolutionary biology; Ecology; Genetics; Immunology; Computer science; Gene; Telecommunications","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001395347,0.0003615341,0.0005940055,0.0001503615,0.0001417883,0.00002609596,0.000242019,0.0004561634,0.00002090998],"category_scores_gemma":[0.0001491297,0.0003316537,0.0003963446,0.0003167836,0.00002716273,0.000001402211,0.000104457,0.0001693894,0.00004298775],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001079124,"about_ca_system_score_gemma":0.0002956637,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002372105,"about_ca_topic_score_gemma":0.00001765454,"domain_scores_codex":[0.998354,0.0001160997,0.0004082748,0.0006233015,0.0001708923,0.0003274805],"domain_scores_gemma":[0.9990989,0.00002694668,0.0001211225,0.0004744061,0.0001035765,0.0001750589],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005759432,0.0003666612,0.00007278598,0.02344563,0.0007331176,0.00002076069,0.0001702708,0.0003761909,0.009917237,0.0007291549,0.005115684,0.9589949],"study_design_scores_gemma":[0.0001474422,0.0001544315,0.0000194042,0.005138865,0.0006482003,0.00001207149,0.00006913398,0.0001169633,0.00006369225,0.00007447534,0.993003,0.0005523913],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009633465,0.9549906,0.04135615,0.00002672707,0.000226224,0.0006892977,0.0001663542,0.00003302477,0.002415301],"genre_scores_gemma":[0.0001518207,0.99069,0.001414499,0.00005794357,0.0002691248,0.00004625078,0.0007065834,0.00004809741,0.006615703],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9878873,"threshold_uncertainty_score":0.9999136,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02459114135096672,"score_gpt":0.3202715897678681,"score_spread":0.2956804484169014,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}