{"id":"W4408884501","doi":"10.1080/03079457.2025.2476511","title":"The host protein CCT8 interacts with PB2 protein of H9N2 AIV and facilitates virus replication","year":2025,"lang":"en","type":"article","venue":"Avian Pathology","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministry of Agriculture","funders":"Priority Academic Program Development of Jiangsu Higher Education Institutions; Ministry of Agriculture and Rural Affairs of the People's Republic of China; National Natural Science Foundation of China","keywords":"Gene knockdown; Virology; Virus; Viral replication; Downregulation and upregulation; Biology; Host (biology); Influenza A virus; Viral protein; Gene; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004833907,0.0001228205,0.0002560012,0.0001091806,0.0001543464,0.00001265323,0.0001091708,0.00007099339,0.00000839895],"category_scores_gemma":[0.001449478,0.0000731767,0.00002803402,0.000202005,0.0006474865,0.00005037449,0.0001307594,0.0002431823,0.00001610472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003971174,"about_ca_system_score_gemma":0.00009859195,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008257117,"about_ca_topic_score_gemma":0.0001142233,"domain_scores_codex":[0.9988729,0.0001443832,0.0002576538,0.0003191759,0.0001486761,0.0002572163],"domain_scores_gemma":[0.9988591,0.000152893,0.00008989521,0.0005991602,0.0002532208,0.00004574223],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00141958,0.0001187093,0.010704,0.0003308088,0.0001270916,0.0001016369,0.001572222,3.170334e-7,0.9568232,0.00349892,0.0002795906,0.02502386],"study_design_scores_gemma":[0.002566629,0.002197517,0.3588182,0.0006404762,0.00006538214,0.0001026021,0.001366892,0.00002497878,0.6042925,0.001684127,0.02805092,0.0001897577],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888116,0.001420106,0.00007977962,0.004925265,0.00001782555,0.001757995,0.00001901544,0.0000323782,0.002936039],"genre_scores_gemma":[0.9944295,0.00008973874,0.0006712315,0.0003693923,0.00001549025,0.0005743544,0.000005677293,0.00001007221,0.00383455],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3525307,"threshold_uncertainty_score":0.2984059,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02847715559505945,"score_gpt":0.3458983288002148,"score_spread":0.3174211732051554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}