{"id":"W4408884506","doi":"10.1007/5584_2025_854","title":"Advances in Regenerative Medicine, Cell Therapy, and 3D Bioprinting for Glaucoma and Retinal Diseases","year":2025,"lang":"en","type":"review","venue":"Advances in experimental medicine and biology","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Dalhousie University; Queen's University; McGill University Health Centre; Université de Sherbrooke","funders":"","keywords":"Regenerative medicine; Induced pluripotent stem cell; Medicine; Neuroscience; Glaucoma; 3D bioprinting; Stem-cell therapy; Stem cell; Retinal; Embryonic stem cell; Macular degeneration; Mesenchymal stem cell; Ophthalmology; Tissue engineering; Pathology; Biology; Biomedical engineering; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007566178,0.0009636552,0.001497033,0.002120136,0.0002499038,0.001094381,0.0009450705,0.001081259,0.006610124],"category_scores_gemma":[0.000783422,0.0002552636,0.0005594365,0.001937531,0.0004288287,0.001322449,0.000898899,0.002202295,0.002844373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005553624,"about_ca_system_score_gemma":0.0009149946,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009486222,"about_ca_topic_score_gemma":0.002291959,"domain_scores_codex":[0.9998003,0.00002654305,0.0000216741,0.00003146134,0.00009490647,0.00002520043],"domain_scores_gemma":[0.9997054,0.0001482476,0.0000332133,0.0000100874,0.00007299386,0.00003004953],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008685119,0.00007254198,0.00007479411,0.01230155,0.00006716955,0.0001534588,0.00002987401,0.0003368081,0.002778211,0.005040319,0.03752301,0.9415354],"study_design_scores_gemma":[0.00002228896,0.00006708714,0.0003484487,0.0021566,0.0000891953,0.0004998912,0.00002559141,0.0001053733,0.0006784161,0.002239476,0.9937511,0.00001651391],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006910456,0.9981511,0.0002292987,0.0002183858,0.0002999062,0.00000418158,0.00002368488,0.00001078291,0.0009934766],"genre_scores_gemma":[0.000417182,0.9980904,0.0003028551,0.0001912544,0.0002068971,0.000005620742,0.00003850014,0.00000246041,0.0007448483],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006610124,"threshold_uncertainty_score":0.02211308,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02454080769105629,"score_gpt":0.3792596051342466,"score_spread":0.3547187974431903,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}