{"id":"W4408884506","doi":"10.1007/5584_2025_854","title":"Advances in Regenerative Medicine, Cell Therapy, and 3D Bioprinting for Glaucoma and Retinal Diseases","year":2025,"lang":"en","type":"review","venue":"Advances in experimental medicine and biology","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Dalhousie University; Queen's University; McGill University Health Centre; Université de Sherbrooke","funders":"","keywords":"Regenerative medicine; Induced pluripotent stem cell; Medicine; Neuroscience; Glaucoma; 3D bioprinting; Stem-cell therapy; Stem cell; Retinal; Embryonic stem cell; Macular degeneration; Mesenchymal stem cell; Ophthalmology; Tissue engineering; Pathology; Biology; Biomedical engineering; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001629437,0.0003688076,0.0009030987,0.0001810917,0.00006584388,0.000005366242,0.0001140203,0.0002035965,0.000006697095],"category_scores_gemma":[0.0001254673,0.000246222,0.00004120906,0.0001304287,0.0006814352,0.00001453554,0.0001312814,0.0001119684,9.578632e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000139299,"about_ca_system_score_gemma":0.00004996944,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001782862,"about_ca_topic_score_gemma":0.00004286933,"domain_scores_codex":[0.998459,0.0001208051,0.0004625643,0.0006515767,0.00004827943,0.0002577198],"domain_scores_gemma":[0.9994273,0.0001900876,0.0001792988,0.0001171849,0.00002142352,0.0000647013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002066319,0.00005582177,0.006003872,0.002769662,0.00001885767,0.000004039458,0.0001980309,4.979573e-8,0.001850884,0.0004129156,0.00007466462,0.9884046],"study_design_scores_gemma":[0.00203747,0.001574525,0.0001114533,0.003964294,0.00004239813,0.00001643191,0.001175569,0.000002796718,0.0006480766,0.0003737975,0.989701,0.000352242],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005053557,0.9925006,0.00005096454,0.00009788831,0.0002090175,0.0006816583,0.00001329357,0.00000519471,0.001387818],"genre_scores_gemma":[0.003443765,0.9949325,0.0005455271,0.0001847074,0.0001933349,0.0002659301,0.0003245586,0.0000145342,0.00009512103],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9896263,"threshold_uncertainty_score":0.999999,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02454080769105629,"score_gpt":0.3792596051342466,"score_spread":0.3547187974431903,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}