{"id":"W4408900249","doi":"10.21037/apm-24-145","title":"Impact of recent clinical trials on meta-analysis of stereotactic body radiation therapy for spine metastases and urgent call for consistent study endpoints","year":2025,"lang":"en","type":"article","venue":"Annals of Palliative Medicine","topic":"Management of metastatic bone disease","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Medicine; Meta-analysis; Clinical trial; SPINE (molecular biology); Radiation therapy; Stereotactic radiation therapy; Stereotactic radiotherapy; Clinical endpoint; Medical physics; Radiosurgery; Radiology; Internal medicine; Bioinformatics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.1492994,0.003622109,0.01690876,0.004328332,0.0009966185,0.00919448,0.003985326,0.005082498,0.004638062],"category_scores_gemma":[0.2851145,0.001968886,0.06734333,0.007735275,0.001835356,0.004543012,0.002612738,0.005754807,0.0005980081],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002566465,"about_ca_system_score_gemma":0.002997343,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004132991,"about_ca_topic_score_gemma":0.006228868,"domain_scores_codex":[0.8280029,0.1279351,0.02563382,0.009088863,0.008126481,0.001212881],"domain_scores_gemma":[0.7487293,0.2135785,0.01686709,0.0127538,0.006625155,0.001446055],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.003537482,0.00001354451,0.004345214,0.04758281,0.9356712,0.0000965912,0.00005971846,0.0007730436,0.0001331892,0.0003874082,0.001398594,0.006001181],"study_design_scores_gemma":[0.001489292,0.0001930886,0.004215039,0.006535821,0.9815961,0.00008314837,0.0000328222,0.0004894247,0.0001677521,0.001554455,0.003613094,0.00002997355],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.00822629,0.9753975,0.005767971,0.003669998,0.00288227,0.0005297745,0.001626281,0.000155838,0.001744052],"genre_scores_gemma":[0.6107364,0.3398809,0.01742515,0.01664164,0.004321286,0.003549787,0.005179765,0.0007674773,0.001497587],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.8507006,"threshold_uncertainty_score":0.7895803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.5978967301219613,"score_gpt":0.5988159128498213,"score_spread":0.0009191827278599574,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}