{"id":"W4408907479","doi":"10.1021/acschembio.4c00788","title":"Structural and Biochemical Insights into Lignin-Oxidizing Activity of Bacterial Peroxidases against Soluble Substrates and Kraft Lignin","year":2025,"lang":"en","type":"article","venue":"ACS Chemical Biology","topic":"Enzyme-mediated dye degradation","field":"Agricultural and Biological Sciences","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Toronto","funders":"H2020 Food; Natural Sciences and Engineering Research Council of Canada; Genome Canada","keywords":"Lignin; Oxidizing agent; Peroxidase; Chemistry; Kraft paper; Biochemistry; Organic chemistry; Lignin peroxidase; Food science; Enzyme; Pulp and paper industry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008135413,0.0001831687,0.000303522,0.0000242399,0.00009185493,0.00002951096,0.0001573574,0.0003413705,0.00001123905],"category_scores_gemma":[0.0001805855,0.00008349591,0.00004061656,0.0002117269,0.0003972263,0.00011235,0.0001999418,0.0001667617,0.000001152728],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001905521,"about_ca_system_score_gemma":0.00001416923,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001347113,"about_ca_topic_score_gemma":0.00006504855,"domain_scores_codex":[0.9989693,0.00007424505,0.0002476073,0.0004070132,0.00006461798,0.0002372462],"domain_scores_gemma":[0.9992087,0.0004865243,0.00009824369,0.000060193,0.00005983798,0.00008652189],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004211288,0.00002848205,0.004094917,0.00001774637,0.00002055433,6.883774e-7,0.00006013054,3.427471e-8,0.9887738,0.0003055747,0.0001876267,0.006468343],"study_design_scores_gemma":[0.0002659493,0.00009234791,0.006409923,0.00002755917,0.0000151322,0.000002013509,0.00007513935,0.00002734496,0.9912236,0.00145146,0.0002589181,0.0001506292],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983328,0.0008286716,3.474769e-7,0.0004688559,0.0001210082,0.0001238927,0.00001700573,0.00004316385,0.00006426949],"genre_scores_gemma":[0.9990953,0.0002142668,0.0001642036,0.00009520283,0.0001230633,0.00000901059,0.0002879108,0.000001152461,0.000009896791],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006317713,"threshold_uncertainty_score":0.3404864,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01121389309671876,"score_gpt":0.228523246682464,"score_spread":0.2173093535857452,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}