{"id":"W4408919769","doi":"10.21037/jtd-2024-2100","title":"When to initiate durvalumab after concurrent chemoradiation in unresectable stage III non-small cell lung cancer?—A commentary on the phase II TORG 1937 (DATE) study","year":2025,"lang":"en","type":"letter","venue":"Journal of Thoracic Disease","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"London Health Sciences Centre; Occupational Cancer Research Centre; Western University","funders":"","keywords":"Durvalumab; Medicine; Stage (stratigraphy); Lung cancer; Oncology; Cancer; Internal medicine; Biology; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00642395,0.0005687916,0.001704427,0.0005956296,0.001835519,0.002679166,0.001828771,0.02620503,0.006477066],"category_scores_gemma":[0.02048838,0.0005204612,0.001712335,0.0007912646,0.001416072,0.002448478,0.0008925883,0.02458786,0.004599968],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004900394,"about_ca_system_score_gemma":0.005004262,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006107268,"about_ca_topic_score_gemma":0.0208186,"domain_scores_codex":[0.9966612,0.00155081,0.0003681756,0.0003174398,0.0007224079,0.0003799738],"domain_scores_gemma":[0.9886847,0.007073998,0.0007936137,0.0002379556,0.001286548,0.001923064],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006927585,0.00004957719,0.0006747357,0.0001261624,0.00005571641,0.0002698892,0.00004365086,0.000116011,0.0001943272,0.001773227,0.9707197,0.02528427],"study_design_scores_gemma":[0.002435976,0.0005459511,0.002647592,0.001205069,0.0003276558,0.0007532307,0.0002599258,0.0007887973,0.0005312356,0.01017719,0.98022,0.0001074724],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0005943411,0.003814405,0.0000792759,0.9680999,0.02391786,0.00001722328,0.0002498247,0.00001934507,0.003207793],"genre_scores_gemma":[0.004548098,0.001688869,0.0002114673,0.9616676,0.02915876,0.00004197842,0.0000975884,0.00002321255,0.002562498],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02620503,"threshold_uncertainty_score":0.03555501,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02166280775284219,"score_gpt":0.385070673425193,"score_spread":0.3634078656723508,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}