{"id":"W4408937309","doi":"10.1016/j.jpet.2024.100536","title":"Investigating the Effects of Jadomycin B Combined with Celecoxib Against Triple-Negative Breast Cancer Modeled with Zebrafish Xenografts (Abstract ID: 157666)","year":2025,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"National Research Council Canada; Dalhousie University","funders":"","keywords":"Celecoxib; Zebrafish; Triple-negative breast cancer; Triple negative; Cancer research; Breast cancer; Cancer; Medicine; Internal medicine; Oncology; Chemistry; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009347588,0.0002001841,0.0003178877,0.00003649167,0.0002058039,0.00002061986,0.0002152081,0.00009487082,0.00008692549],"category_scores_gemma":[0.000004737227,0.0001254493,0.00005849986,0.0001716765,0.0004316,0.00009627543,0.0000377492,0.0004514632,1.8298e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007361966,"about_ca_system_score_gemma":0.0001795268,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001273187,"about_ca_topic_score_gemma":0.000002935284,"domain_scores_codex":[0.9991228,0.00003613127,0.0003616145,0.0001465147,0.0001462312,0.0001867092],"domain_scores_gemma":[0.9988277,0.0004033959,0.0004803505,0.0001003161,0.0001182271,0.0000700235],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001185227,0.0004907717,0.001497084,0.0001556225,0.000915406,0.000008184241,0.001035481,0.0001778355,0.993294,0.00004217921,0.00040097,0.0007972229],"study_design_scores_gemma":[0.006196415,0.0001613128,0.0005369743,0.0002093769,0.0003274285,0.00005117499,0.001376653,0.0003983507,0.9902648,0.00008362961,0.0002622628,0.0001316337],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964288,0.001335492,0.00001940522,0.00121169,0.00009374169,0.0001706205,0.00002201792,0.00001170735,0.0007065298],"genre_scores_gemma":[0.9979529,0.0002679091,0.0001526086,0.001323805,0.0001189613,0.00005504312,0.00000393405,0.00001496796,0.0001098226],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005011188,"threshold_uncertainty_score":0.5115672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01205540131623658,"score_gpt":0.3090339710997158,"score_spread":0.2969785697834792,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}