{"id":"W4408958425","doi":"10.1007/s10600-025-04634-1","title":"Transformation of 5α-Pregnenolone Into Some Hydrazones: Synthesis and Biological Activity","year":2025,"lang":"en","type":"article","venue":"Chemistry of Natural Compounds","topic":"Steroid Chemistry and Biochemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université du Québec à Chicoutimi","funders":"","keywords":"Chemistry; Transformation (genetics); Pregnenolone; Organic chemistry; Combinatorial chemistry; Biochemistry; Steroid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001183004,0.0002133338,0.000312665,0.00002164978,0.00006554151,0.00001073425,0.0002721769,0.0003519266,0.00000921813],"category_scores_gemma":[0.0001490069,0.0001932266,0.0001316913,0.0001140622,0.0003496357,0.00001043138,0.0001348821,0.0001671798,2.372793e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001934981,"about_ca_system_score_gemma":0.00005505721,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007803253,"about_ca_topic_score_gemma":5.511031e-7,"domain_scores_codex":[0.9990515,0.00002249914,0.0003006178,0.000332772,0.0001167246,0.0001758884],"domain_scores_gemma":[0.9993152,0.00005688737,0.0001573079,0.0003232255,0.00009548244,0.0000518654],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000301336,0.00009606507,0.0006576853,0.000757852,0.00009591548,6.664373e-7,0.000029699,0.000001552059,0.9957629,0.00001075785,0.0001420476,0.002143478],"study_design_scores_gemma":[0.000455004,0.00003958334,0.001337983,0.0001183079,0.00003455548,0.00001537881,0.000098549,0.00004091882,0.9969687,0.0001672879,0.0005430413,0.0001807334],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950081,0.002810109,0.00005388955,0.0002130078,0.00005540407,0.00007302237,0.00002704913,0.00001476935,0.001744723],"genre_scores_gemma":[0.9989815,0.0003238757,0.0001637794,0.00002970775,0.00006820184,0.00001244446,0.00009599159,0.000006905361,0.0003175426],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003973525,"threshold_uncertainty_score":0.7879553,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007787377691718765,"score_gpt":0.2413354407537591,"score_spread":0.2335480630620403,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}