{"id":"W4408960968","doi":"10.2337/dc25-0241","title":"Cardiovascular and Kidney Outcomes and Mortality With Long-Acting Injectable and Oral Glucagon-Like Peptide 1 Receptor Agonists in Individuals With Type 2 Diabetes: A Systematic Review and Meta-analysis of Randomized Trials","year":2025,"lang":"en","type":"review","venue":"Diabetes Care","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Medicine; Meta-analysis; Randomized controlled trial; Type 2 diabetes; Internal medicine; Diabetes mellitus; Glucagon-like peptide-1; Systematic review; MEDLINE; Glucagon-like peptide 1 receptor; Endocrinology; Receptor; Agonist","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaepi_broad"],"consensus_categories":[],"category_scores_codex":[0.01712942,0.002782717,0.02199509,0.007454516,0.000554722,0.002943598,0.002407974,0.002000301,0.00394946],"category_scores_gemma":[0.03966649,0.001460032,0.03480811,0.009347524,0.0007716759,0.001711114,0.001492076,0.001655818,0.0003207774],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002788259,"about_ca_system_score_gemma":0.004665134,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006693149,"about_ca_topic_score_gemma":0.01415168,"domain_scores_codex":[0.9872934,0.005584844,0.004081782,0.001326667,0.00137292,0.0003404843],"domain_scores_gemma":[0.9740951,0.01843614,0.005011128,0.0007010908,0.001505053,0.0002515372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.00121597,0.00001787585,0.002298057,0.5884028,0.3970249,0.0000786611,0.00006240993,0.0004767132,0.00013017,0.0001069936,0.0006657104,0.009519742],"study_design_scores_gemma":[0.0008377291,0.000171632,0.002900242,0.05446446,0.9393233,0.00007762526,0.00004094904,0.0001579293,0.00009203251,0.0002203496,0.001686298,0.00002744146],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003276623,0.9939319,0.0006193091,0.000219315,0.0001233326,0.0004997653,0.001054185,0.00002953198,0.0002461413],"genre_scores_gemma":[0.1169176,0.8742561,0.003038329,0.00114653,0.0002605552,0.00271678,0.001316584,0.00003673372,0.0003107481],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9780049,"threshold_uncertainty_score":0.09059012,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05742783141103074,"score_gpt":0.3387007941500514,"score_spread":0.2812729627390207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}