{"id":"W4408964562","doi":"10.1016/s0735-1097(25)02990-0","title":"CARDIOVASCULAR RISK OF BRUTON’S TYROSINE KINASE INHIBITORS: A SYSTEMATIC REVIEW AND NETWORK META-ANALYSIS","year":2025,"lang":"en","type":"review","venue":"Journal of the American College of Cardiology","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Medicine; Meta-analysis; Tyrosine kinase; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004612818,0.001988744,0.01152734,0.002583837,0.0004230772,0.001915368,0.001323078,0.001758029,0.004016576],"category_scores_gemma":[0.01120935,0.001274848,0.0231478,0.003710403,0.0004592676,0.001163668,0.00136916,0.002078897,0.0003329691],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001239717,"about_ca_system_score_gemma":0.001673101,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006273668,"about_ca_topic_score_gemma":0.01766997,"domain_scores_codex":[0.9971792,0.001141838,0.0007532922,0.0004488994,0.0003017248,0.000175082],"domain_scores_gemma":[0.9943516,0.003912002,0.001014774,0.0002330989,0.0003740127,0.0001144975],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.003440985,0.0000498566,0.005985735,0.2310089,0.7415094,0.0001404814,0.00006884891,0.000587607,0.000371205,0.0001259316,0.001088088,0.01562295],"study_design_scores_gemma":[0.000850368,0.0001647633,0.004783174,0.00871046,0.9834967,0.00006802742,0.00003443292,0.0001508299,0.0000705431,0.0001563434,0.00148851,0.00002590831],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.007300592,0.991007,0.000489464,0.0001610041,0.0001482977,0.0001060344,0.0005344014,0.00002378902,0.0002293641],"genre_scores_gemma":[0.2095147,0.7856862,0.001839285,0.001108566,0.0003031056,0.0003229279,0.0007142924,0.00003058777,0.000480247],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01152734,"threshold_uncertainty_score":0.02439523,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03054202153416962,"score_gpt":0.3062670778825295,"score_spread":0.2757250563483599,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}