{"id":"W4408980368","doi":"10.1016/j.neuropharm.2025.110436","title":"Fatty acid amide hydrolase in comorbid borderline personality disorder and major depressive disorder: Imaging with [11C]CURB PET","year":2025,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Neurotransmitter Receptor Influence on Behavior","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute; University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Fatty acid amide hydrolase; Borderline personality disorder; Hydrolase; Major depressive disorder; Psychology; Pet imaging; Clinical psychology; Psychiatry; Medicine; Internal medicine; Positron emission tomography; Biochemistry; Neuroscience; Chemistry; Enzyme; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001353563,0.0004648709,0.0004835067,0.0003453222,0.0002931763,0.00008798356,0.0005585428,0.00006267902,0.0003312364],"category_scores_gemma":[0.0001790451,0.0004319752,0.00006829049,0.0007396907,0.0007736994,0.0003879981,0.0002621883,0.0009561144,0.00003574213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005345641,"about_ca_system_score_gemma":0.0001064479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002550113,"about_ca_topic_score_gemma":0.0002011053,"domain_scores_codex":[0.9964216,0.0007353071,0.0004789977,0.001294303,0.0003038377,0.0007658959],"domain_scores_gemma":[0.9987463,0.0004667826,0.0001590618,0.00038998,0.00005864863,0.000179208],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004479324,0.0004069406,0.308596,0.00006075544,0.000006044077,0.001595162,0.00009750209,0.00008512117,0.6851959,0.00007431897,0.0000881868,0.003346095],"study_design_scores_gemma":[0.01527496,0.0003971993,0.3797645,0.00007798296,0.0002429583,0.0008220451,0.00008356239,0.00422506,0.5849902,0.000120153,0.01298895,0.001012446],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930279,0.0002937011,0.0001628661,0.004420509,0.0003910615,0.0009838024,0.00007911062,0.0001816284,0.0004594423],"genre_scores_gemma":[0.9895436,0.0002295717,0.0001082294,0.009606529,0.00002935618,0.0002712175,0.000005542227,0.00006039125,0.0001455967],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1002057,"threshold_uncertainty_score":0.9998132,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01225935007606932,"score_gpt":0.2994859177177128,"score_spread":0.2872265676416434,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}