{"id":"W4408982662","doi":"10.1016/j.vetimm.2025.110926","title":"Blood and colostral IgM and IgG B cell repertoires in high, average, and low immune responder Holstein Friesian cows and heifers","year":2025,"lang":"en","type":"article","venue":"Veterinary Immunology and Immunopathology","topic":"Reproductive Physiology in Livestock","field":"Agricultural and Biological Sciences","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo; University of Guelph","funders":"Alliance de recherche numérique du Canada; Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Agriculture, Food and Rural Affairs; University of Guelph","keywords":"Biology; Immune system; Antibody; Holstein Cattle; B cell; Colostrum; Immunology; Animal science; Andrology; Dairy cattle; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002301683,0.0001262271,0.0001819232,0.0006740245,0.0002299086,0.0002727461,0.0001370173,0.0001986146,0.0005277374],"category_scores_gemma":[0.0003885255,0.000120244,0.00009608024,0.0002823989,0.0002533913,0.000114001,0.0001322298,0.0001937487,0.0001081477],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002005289,"about_ca_system_score_gemma":0.00007970888,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001897465,"about_ca_topic_score_gemma":0.002425951,"domain_scores_codex":[0.9997999,0.00004697165,0.00001356109,0.00004983478,0.0000378917,0.00005184173],"domain_scores_gemma":[0.9997708,0.00006324035,0.00007738444,0.00001204757,0.00002078175,0.00005581936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002111955,0.0001414184,0.7093042,0.00004322837,0.0000798882,0.0002835455,0.00116124,0.0001113649,0.2765787,0.00005325235,0.00006864911,0.01006253],"study_design_scores_gemma":[0.000006845742,0.000250449,0.9969816,0.000002792796,0.00001852487,0.0002324642,0.0002501489,0.0001093616,0.002039375,0.0000135888,0.00009287492,0.000001982696],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9998616,0.00004536006,0.00002104387,0.000001634719,2.595092e-7,5.578844e-7,0.000019823,5.144317e-7,0.00004918888],"genre_scores_gemma":[0.999523,0.00004734027,0.0001148005,0.00001393854,0.000001984364,0.000002915285,0.0001219033,0.000001094012,0.0001728513],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001897465,"threshold_uncertainty_score":0.003772795,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008361519453824996,"score_gpt":0.2145222572820029,"score_spread":0.2061607378281779,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}