{"id":"W4408985065","doi":"10.1016/j.clml.2025.03.014","title":"Outcomes of Patients With Extramedullary Disease in Triple-Class Exposed Relapsed/Refractory Multiple Myeloma From the Pooled LocoMMotion and MoMMent Studies","year":2025,"lang":"en","type":"article","venue":"Clinical Lymphoma Myeloma & Leukemia","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"Legend Biotech; Johnson and Johnson","keywords":"Medicine; Multiple myeloma; Refractory (planetary science); Oncology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01422715,0.0009744574,0.002399797,0.002599874,0.0002626509,0.001224037,0.000704916,0.0006009037,0.000932151],"category_scores_gemma":[0.009734086,0.0004497661,0.006780372,0.002584974,0.0003019347,0.0006249734,0.001597686,0.0004204672,0.0001149121],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006402264,"about_ca_system_score_gemma":0.0004235261,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00129018,"about_ca_topic_score_gemma":0.002803177,"domain_scores_codex":[0.993517,0.00341838,0.001233457,0.0008731221,0.000744455,0.0002134648],"domain_scores_gemma":[0.9894499,0.00283106,0.005534685,0.0009858473,0.0008769509,0.0003214873],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01977141,0.00006984378,0.8330597,0.003393827,0.1145143,0.0002102717,0.0001974007,0.0009819524,0.0009942445,0.000112558,0.001127805,0.02556665],"study_design_scores_gemma":[0.001140031,0.001681769,0.936273,0.0004283163,0.05701109,0.0004792928,0.0001376123,0.0003435961,0.0004131553,0.0001234382,0.001925661,0.00004308512],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9206755,0.06990123,0.001022207,0.0002657133,0.00005629232,0.0001647867,0.006571577,0.00003710773,0.001305504],"genre_scores_gemma":[0.9914278,0.003660423,0.0002558495,0.0001768793,0.00007570734,0.0000949657,0.004196724,0.000009173925,0.0001023295],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01422715,"threshold_uncertainty_score":0.07524127,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03591341014526184,"score_gpt":0.3351751832576492,"score_spread":0.2992617731123874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}