{"id":"W4409001242","doi":"10.3390/v17040503","title":"Cyclooxygenase-2/Prostaglandin E2 Pathway Facilitates Infectious Bronchitis Virus-Induced Necroptosis in Chicken Macrophages, a Caspase-Independent Cell Death","year":2025,"lang":"en","type":"article","venue":"Viruses","topic":"Animal Virus Infections Studies","field":"Agricultural and Biological Sciences","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Necroptosis; Programmed cell death; Apoptosis; Biology; Inflammasome; Coronavirus; Viral replication; Caspase; Virology; Cell biology; Virus; Immunology; Inflammation; Medicine; Coronavirus disease 2019 (COVID-19); Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001069377,0.0002578225,0.0001512039,0.0001080803,0.0001151819,0.0002068177,0.00007449766,0.0002086874,0.0006039024],"category_scores_gemma":[0.00004962894,0.00007697636,0.0001782664,0.00005986994,0.0001654502,0.0001643965,0.0001350475,0.0003798505,0.0001222879],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000190391,"about_ca_system_score_gemma":0.0001685082,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003851611,"about_ca_topic_score_gemma":0.000996782,"domain_scores_codex":[0.9999253,0.00001681841,0.000007113284,0.00001553072,0.00001351753,0.00002178507],"domain_scores_gemma":[0.999965,0.000004837485,0.00001203154,0.000003961014,0.000005843686,0.00000833604],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001566287,0.0000224593,0.0003836175,0.00005326655,0.000003794883,0.00006985868,0.00001253024,0.00003594868,0.9984433,0.00003625116,0.00001856475,0.0007637657],"study_design_scores_gemma":[0.00003527869,0.000591361,0.01590584,0.00001252339,0.00001972346,0.0003833363,0.0001202983,0.0006578667,0.9803481,0.00006114301,0.00185946,0.000005056753],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957312,0.001891997,0.0009902844,0.00009841247,0.00002346869,0.00002763745,0.0001788602,0.00001989374,0.001038102],"genre_scores_gemma":[0.9967391,0.0009272,0.000843076,0.00004652108,0.000006810817,0.00002916993,0.0001773585,0.00000298097,0.001227938],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006039024,"threshold_uncertainty_score":0.002020299,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02356000417394548,"score_gpt":0.2453823443088484,"score_spread":0.2218223401349029,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}