{"id":"W4409017737","doi":"10.1016/j.fbio.2025.106450","title":"Immune restoration mechanism analysis of Akkermansia PROBIO in mice treated with cyclophosphamide through Re-balancing microbiota composition","year":2025,"lang":"en","type":"article","venue":"Food Bioscience","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Akkermansia; Mechanism (biology); Cyclophosphamide; Immune system; Composition (language); Immunology; Biology; Chemistry; Bacteria; Genetics; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002274623,0.0001298936,0.0002223711,0.0001933962,0.00012142,0.00001895934,0.0001923261,0.0001146968,0.000002150162],"category_scores_gemma":[0.00001156987,0.0001142265,0.00005826665,0.001545692,0.0001089438,0.0000118847,0.00005657188,0.0000927601,8.713907e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005621107,"about_ca_system_score_gemma":0.0001409548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004357617,"about_ca_topic_score_gemma":0.001097943,"domain_scores_codex":[0.9989755,0.00008135986,0.0002976389,0.0003511144,0.00007617144,0.0002182298],"domain_scores_gemma":[0.9994538,0.000008337819,0.0001500625,0.0002711195,0.00009325108,0.00002337335],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009884049,0.00009485348,0.003501425,0.00004067699,0.00006810958,8.032575e-7,0.0001672669,0.0001312721,0.9955594,0.0002679569,0.00003729898,0.00003209444],"study_design_scores_gemma":[0.000399273,0.0004626111,0.07824345,0.00008915224,0.00009745062,0.000002349459,0.0001237235,0.00009961398,0.9202204,0.00002764293,0.0001144352,0.0001198431],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959814,0.0002637806,0.002970306,0.0001855728,0.00005383021,0.0002681097,0.00004165242,0.00001055301,0.0002248208],"genre_scores_gemma":[0.997787,0.00004512408,0.001589826,0.0002301774,0.000006882855,0.00000877062,0.000233066,0.000005680275,0.00009347274],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07533894,"threshold_uncertainty_score":0.4658023,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006941683918638614,"score_gpt":0.2472420642221078,"score_spread":0.2403003803034692,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}