{"id":"W4409020822","doi":"10.1371/journal.pgen.1011629","title":"Gene expression in soft-shell clam (Mya arenaria) transmissible cancer reveals survival mechanisms during host infection and seawater transfer","year":2025,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Prince Edward Island","funders":"National Institute of General Medical Sciences; National Human Genome Research Institute; National Cancer Institute; Foundation for the National Institutes of Health","keywords":"Biology; Population; Transcriptome; Gene; Lineage (genetic); Cancer; Genetics; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007877107,0.0001444884,0.0001437965,0.0003656142,0.0001406582,0.0002594985,0.00008935326,0.0002373742,0.0004658208],"category_scores_gemma":[0.0001163025,0.0001001726,0.0001820284,0.0002633483,0.0001802568,0.0001428036,0.0002155177,0.0002449824,0.0001259753],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001727436,"about_ca_system_score_gemma":0.0001233626,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000946732,"about_ca_topic_score_gemma":0.001746777,"domain_scores_codex":[0.9999226,0.000005150005,0.000004179114,0.00003287033,0.00001632749,0.00001888287],"domain_scores_gemma":[0.9999121,0.00001275194,0.00003158948,0.000007119984,0.00001775602,0.00001859279],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006796371,0.000007877432,0.004533849,0.00001355417,0.000004032221,0.00003177907,0.00007383219,0.00003573378,0.9942925,0.00003016651,0.00001340809,0.0008953317],"study_design_scores_gemma":[0.00001626672,0.0006565013,0.7016988,0.00002167633,0.00005105833,0.0003675381,0.0007467,0.002268934,0.2919551,0.0001927316,0.002006972,0.00001779618],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984983,0.0002883387,0.0003929316,0.00002430644,0.000002444032,0.000005662355,0.0004559363,0.00001371705,0.0003183241],"genre_scores_gemma":[0.9960907,0.0002394888,0.0009682466,0.00007425295,0.000004220229,0.00003303512,0.001018391,0.00001058574,0.001560854],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000946732,"threshold_uncertainty_score":0.001882493,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01574773474602581,"score_gpt":0.2770750426290625,"score_spread":0.2613273078830367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}