{"id":"W4409037925","doi":"10.1016/j.bpsgos.2025.100496","title":"Astrogliosis Occurs Selectively in Amygdala of Adolescent Primate and Rodent Following Daily Δ9-Tetrahydrocannabinol, Prevented by Cannabidiol Co-Treatment","year":2025,"lang":"en","type":"article","venue":"Biological Psychiatry Global Open Science","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Institute on Drug Abuse; Canadian Institutes of Health Research","keywords":"Cannabidiol; Astrogliosis; Primate; Tetrahydrocannabinol; Amygdala; Δ9-tetrahydrocannabinol; Pharmacology; Rodent; Psychology; Cannabis; Neuroscience; Medicine; Cannabinoid; Biology; Internal medicine; Psychiatry; Central nervous system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005880912,0.0002712115,0.0002366616,0.0002828683,0.0002796713,0.0002090046,0.0002050652,0.0002111104,0.001734964],"category_scores_gemma":[0.00006821186,0.0002092487,0.0002058633,0.0001081336,0.0003033911,0.0001360955,0.0001758557,0.0004746447,0.0003355505],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003022576,"about_ca_system_score_gemma":0.0003065966,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002709731,"about_ca_topic_score_gemma":0.01009149,"domain_scores_codex":[0.9999115,0.000005965117,0.000004783617,0.00002977517,0.00002428121,0.00002360411],"domain_scores_gemma":[0.9999381,0.000002538777,0.0000190576,0.000007734563,0.00001135061,0.00002118003],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002192733,0.00003730016,0.0008686735,0.00004059472,0.00001029972,0.0001791993,0.00008163857,0.000009423999,0.9971634,0.00004569985,0.00006960391,0.001274837],"study_design_scores_gemma":[0.0000349953,0.001439447,0.1257965,0.00004687231,0.0001183323,0.00229002,0.0005454583,0.0004094949,0.8639312,0.0001613671,0.005208845,0.00001741366],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960323,0.001314666,0.0005542586,0.00007414811,0.00002722325,0.00003026564,0.0003799201,0.00005203486,0.001535112],"genre_scores_gemma":[0.9924538,0.001389891,0.000949341,0.00007916394,0.00001130591,0.0000814868,0.0006216583,0.000027541,0.004385767],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002709731,"threshold_uncertainty_score":0.005804062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02137352817682545,"score_gpt":0.3851082934957056,"score_spread":0.3637347653188802,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}