{"id":"W4409047944","doi":"10.1097/hep.0000000000001334","title":"Getting to HBV cure—Will new biomarkers help?","year":2025,"lang":"en","type":"article","venue":"Hepatology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Toronto Liver Centre; University Health Network","funders":"","keywords":"cccDNA; HBcAg; Medicine; Hepatitis B virus; Hepatitis B; Clinical trial; Immunology; Entecavir; Antigen; Serology; HBsAg; Virology; Lamivudine; Virus; Internal medicine; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01334333,0.000979619,0.002896876,0.00190788,0.000618808,0.005033751,0.001195641,0.00429881,0.007643736],"category_scores_gemma":[0.02061612,0.0003308156,0.001153747,0.001281923,0.003209874,0.01161857,0.00176378,0.006643633,0.00368114],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001591202,"about_ca_system_score_gemma":0.002984849,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009197723,"about_ca_topic_score_gemma":0.001219491,"domain_scores_codex":[0.9973392,0.001415616,0.0002916906,0.0002202701,0.0005370605,0.0001962964],"domain_scores_gemma":[0.9861895,0.007927761,0.001007136,0.0005764789,0.003209772,0.00108921],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007318612,0.0002300152,0.003758355,0.007212617,0.0002526625,0.0003287088,0.0003607909,0.0002465146,0.001842447,0.03858892,0.1387982,0.8076489],"study_design_scores_gemma":[0.000173992,0.0008083352,0.002812505,0.01217621,0.0002752791,0.001022525,0.00113556,0.0003366912,0.001225041,0.06921566,0.9106774,0.0001407459],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.0009041828,0.8443467,0.001521474,0.14294,0.007084975,0.00003818492,0.0001450741,0.00006851578,0.002950965],"genre_scores_gemma":[0.01418988,0.896969,0.007496735,0.05919245,0.01756299,0.0001853795,0.0003112072,0.00005558475,0.004036806],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.01334333,"threshold_uncertainty_score":0.07056713,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02135776373530832,"score_gpt":0.3190040071994641,"score_spread":0.2976462434641558,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}